KEGG   MODULE: M00346
Entry
M00346            Pathway   Module                                 
Name
Formaldehyde assimilation, serine pathway
Definition
K00600 K00830 K00018 K11529 K01689 K01595 K00024 K08692+K14067 K08691
Diagram
M00346  Formaldehyde assimilation, serine pathway
M00346

Class
Pathway modules; Energy metabolism; Methane metabolism
Pathway
map00680  Methane metabolism
map01200  Carbon metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Orthology
K00600  
glycine hydroxymethyltransferase [EC:2.1.2.1] [RN:R00945]
K00830  
serine--glyoxylate transaminase [EC:2.6.1.45] [RN:R00588]
K00018  
glycerate dehydrogenase [EC:1.1.1.29] [RN:R01388]
K11529  
glycerate 2-kinase [EC:2.7.1.165] [RN:R08572]
K01689  
enolase [EC:4.2.1.11] [RN:R00658]
K01595  
phosphoenolpyruvate carboxylase [EC:4.1.1.31] [RN:R00345]
K00024  
malate dehydrogenase [EC:1.1.1.37] [RN:R00342]
K08692,K14067  
malate-CoA ligase [EC:6.2.1.9] [RN:R01256]
K08691  
malyl-CoA lyase [EC:4.1.3.24] [RN:R00473]
Complete
mpt  Methylibium petroleiphilum
metp  Methylibium sp. Pch-M
neu  Nitrosomonas europaea
net  Nitrosomonas eutropha
nit  Nitrosomonas sp. AL212
nii  Nitrosomonas sp. Is79A3
nco  Nitrosomonas communis
nur  Nitrosomonas ureae
nst  Nitrosomonas stercoris
nmu  Nitrosospira multiformis
nlc  Nitrosospira lacus
niz  Nitrosospira sp. NRS527
metr  Methyloversatilis sp. RAC08
fmy  Ferrovum myxofaciens
mea  Methylorubrum extorquens AM1
mdi  Methylorubrum extorquens DM4
mex  Methylorubrum extorquens PA1
mch  Methylorubrum extorquens CM4
mpo  Methylorubrum populi
metq  Methylorubrum sp. GM97
mrd  Methylobacterium radiotolerans
met  Methylobacterium sp. 4-46
mno  Methylobacterium nodulans
mor  Methylobacterium oryzae
meta  Methylobacterium sp. AMS5
maqu  Methylobacterium aquaticum
mphy  Methylobacterium phyllosphaerae
mee  Methylobacterium currus
metd  Methylobacterium sp. DM1
metx  Methylobacterium sp. XJLW
meti  Methylobacterium radiodurans
mtea  Methylobacterium terrae
mind  Methylobacterium indicum
mog  Methylobacterium organophilum
mtad  Methylobacterium tardum
mecl  Methylobacterium sp. CLZ
mfuj  Methylobacterium fujisawaense
meni  Methylobacterium sp. NI91
mens  Methylobacterium sp. NMS14P
mbrc  Methylobacterium brachiatum
msl  Methylocella silvestris
mtun  Methylocella tundrae
mlg  Methylovirgula ligni
mehy  Methylovirgula sp. HY1
medk  Methylocapsa sp. D3K7
mpol  Methylocapsa polymorpha
bbar  Beijerinckiaceae bacterium RH AL1
bbai  Beijerinckiaceae bacterium MG08
mcg  Methyloceanibacter caenitepidi
metg  Methyloligella sp. GL2
msc  Methylocystis hydrogenophila
mbry  Methylocystis bryophila
mros  Methylocystis rosea
mhey  Methylocystis heyeri
mpar  Methylocystis parvus
miwa  Methylocystis iwaonis
mesz  Methylocystis sp. SB2
meci  Methylocystis echinoides
memc  Methylocystis sp. MJC1
mtw  Methylosinus trichosporium
mecq  Methylosinus sp. C49
mspr  Methylosinus sporium
myss  Methylosinus sp. 3S-1
manh  Marinibacterium anthonyi
gbe  Granulibacter bethesdensis CGDNIH1
gbh  Granulibacter bethesdensis CGDNIH2
gbc  Granulibacter bethesdensis NIH3.1
gbs  Granulibacter bethesdensis CGDNIH4
 » show all
Reaction
R00945  
R00588  
R01388  
R08572  
R00658  
R00345  
R00342  
R01256  
R00473  
R00588  
Compound
C00037  Glycine
C00065  L-Serine
C00168  Hydroxypyruvate
C00258  D-Glycerate
C00631  2-Phospho-D-glycerate
C00074  Phosphoenolpyruvate
C00036  Oxaloacetate
C00149  (S)-Malate
C04348  (3S)-3-Carboxy-3-hydroxypropanoyl-CoA
C00048  Glyoxylate
Reference
PMID:16278835
  Authors
Yurimoto H, Kato N, Sakai Y
  Title
Assimilation, dissimilation, and detoxification of formaldehyde, a central metabolic intermediate of methylotrophic metabolism.
  Journal
Chem Rec 5:367-75 (2005)
DOI:10.1002/tcr.20056
Reference
PMID:11920446
  Authors
Van Dien SJ, Lidstrom ME
  Title
Stoichiometric model for evaluating the metabolic capabilities of the facultative methylotroph Methylobacterium extorquens AM1, with application to reconstruction of C(3) and C(4) metabolism.
  Journal
Biotechnol Bioeng 78:296-312 (2002)
DOI:10.1002/bit.10200
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