KEGG   MODULE: M00801
Entry
M00801            Pathway   Module                                 
Name
dTDP-L-olivose biosynthesis
Definition
K16435 K13327 K19858 K13319
Diagram
M00801

Orthology
K16435  
oleV; dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase [EC:4.2.1.159] [RN:R05518]
K13327  
oleW; dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase [EC:1.1.1.384] [RN:R05526]
K19858  
oleL; dTDP-4-oxo-2,6-dideoxy-D-glucose 3,5-epimerase [EC:5.1.3.-] [RN:R08597]
K13319  
oleU; 4-ketoreductase [RN:R06434]
Class
Pathway modules; Biosynthesis of terpenoids and polyketides; Polyketide sugar unit biosynthesis
Pathway
map00523  Polyketide sugar unit biosynthesis
map01250  Biosynthesis of nucleotide sugars
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
Compound
C11907  dTDP-4-oxo-6-deoxy-D-glucose
C06620  dTDP-3,4-dioxo-2,6-dideoxy-D-glucose
C11922  dTDP-4-oxo-2,6-dideoxy-D-glucose
C11927  dTDP-4-oxo-2,6-dideoxy-L-mannose
C11920  dTDP-L-olivose
RModule
RM036  Epimerization and reduction in deoxysugar biosynthesis
RM038  Deoxygenation (dehydration and reduction) in deoxysugar biosynthesis
Reference
  Authors
Aguirrezabalaga I, Olano C, Allende N, Rodriguez L, Brana AF, Mendez C, Salas JA
  Title
Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus.
  Journal
Antimicrob Agents Chemother 44:1266-75 (2000)
DOI:10.1128/AAC.44.5.1266-1275.2000
LinkDB

DBGET integrated database retrieval system