| Entry |
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| Name |
Fosfomycin biosynthesis, phosphoenolpyruvate => fosfomycin
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| Definition |
K23999 K09459 K12901 K12902 K24000 K12903
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| Diagram |
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| Orthology |
fomD; HPP-CMP hydrolase [EC:3.6.1.-] [RN: R12499] fom4; (S)-2-hydroxypropylphosphonic acid epoxidase [EC: 1.11.1.23] [RN: R08863] |
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| Class |
Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of other antibiotics
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| Pathway |
| map00998 | Biosynthesis of various antibiotics |
| map01110 | Biosynthesis of secondary metabolites |
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| Reaction |
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| Compound |
| C06451 | 2-Hydroxyethylphosphonate |
| C22216 | Cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} |
| C22217 | Cytidine 5'-{[hydroxy(2-hydroxypropyl)phosphonoyl]phosphate} |
| C06452 | (S)-2-Hydroxypropylphosphonate |
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| Reference |
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| Authors |
Woodyer RD, Shao Z, Thomas PM, Kelleher NL, Blodgett JA, Metcalf WW, van der Donk WA, Zhao H |
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| Title |
Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster. |
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| Journal |
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| Reference |
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| Authors |
Hidaka T, Goda M, Kuzuyama T, Takei N, Hidaka M, Seto H |
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| Title |
Cloning and nucleotide sequence of fosfomycin biosynthetic genes of Streptomyces wedmorensis. |
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| Journal |
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| LinkDB |
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