KEGG   MODULE: M00911
Entry
M00911            Pathway   Module                                 
Name
Riboflavin biosynthesis, fungi, GTP => riboflavin/FMN/FAD
Definition
K01497 K14654 K14655 --
K02858
K00794 K00793 K00861 K00953
Diagram
M00911  Riboflavin biosynthesis, fungi, GTP => riboflavin/FMN/FAD
M00911

Class
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
Pathway
map00740  Riboflavin metabolism
map01240  Biosynthesis of cofactors
map01100  Metabolic pathways
Orthology
K01497  
GTP cyclohydrolase II [EC:3.5.4.25] [RN:R00425]
K14654  
2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302] [RN:R09375 R09376]
K14655  
2,5-diamino-6-(5-phospho-D-ribitylamino)-pyrimidin-4(3H)-one deaminase [RN:R09377]
K02858  
3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12] [RN:R07281]
K00794  
6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] [RN:R04457]
K00793  
riboflavin synthase [EC:2.5.1.9] [RN:R00066]
K00861  
riboflavin kinase [EC:2.7.1.26] [RN:R00549]
K00953  
FAD synthetase [EC:2.7.7.2] [RN:R00161]
Complete
sce  Saccharomyces cerevisiae (budding yeast)
seub  Saccharomyces eubayanus
spao  Saccharomyces paradoxus
ago  Eremothecium gossypii
erc  Eremothecium cymbalariae
kla  Kluyveromyces lactis
kmx  Kluyveromyces marxianus
lth  Lachancea thermotolerans
vpo  Vanderwaltozyma polyspora
zro  Zygosaccharomyces rouxii
cgr  Nakaseomyces glabratus
ncs  Naumovozyma castellii
ndi  Naumovozyma dairenensis
tpf  Tetrapisispora phaffii
tbl  Henningerozyma blattae
tgb  Torulaspora globosa
tdl  Torulaspora delbrueckii
kaf  Kazachstania africana
kng  Huiozyma naganishii
zmk  Zygotorulaspora mrakii
slud  Saccharomycodes ludwigii
dha  Debaryomyces hansenii
pic  Scheffersomyces stipitis
spaa  Spathaspora passalidarum
lbg  Lodderomyces beijingensis
cot  Lodderomyces orthopsilosis
cal  Candida albicans
ctp  Candida tropicalis
cdu  Candida dubliniensis
cten  Yamadazyma tenuis
clu  Clavispora lusitaniae ATCC 42720
clus  Clavispora lusitaniae CBS 6936
caur  Candidozyma auris
asau  Australozyma saopauloensis
ppa  Komagataella phaffii
pkz  Pichia kudriavzevii
bbrx  Brettanomyces bruxellensis
yli  Yarrowia lipolytica
spo  Schizosaccharomyces pombe (fission yeast)
som  Schizosaccharomyces osmophilus (fission yeast)
hir  Heterobasidion irregulare
 » show all
Reaction
R00425  
R09375,R09376  
R09377  
R07280  
R07281  
R04457  
R00066  
R00549  
R00161  
Compound
C00044  GTP
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C00199  D-Ribulose 5-phosphate
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C00255  Riboflavin
C00061  FMN
C00016  FAD
Reference
PMID:10940330
  Authors
Bacher A, Eberhardt S, Fischer M, Kis K, Richter G
  Title
Biosynthesis of vitamin b2 (riboflavin).
  Journal
Annu Rev Nutr 20:153-67 (2000)
DOI:10.1146/annurev.nutr.20.1.153
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