KEGG   MODULE: M00911
Entry
M00911            Pathway   Module                                 
Name
Riboflavin biosynthesis, fungi, GTP => riboflavin/FMN/FAD
Definition
K01497 K14654 K14655 --
K02858
K00794 K00793 K00861 K00953
Diagram
M00911

Orthology
K01497  
GTP cyclohydrolase II [EC:3.5.4.25] [RN:R00425]
K14654  
2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302] [RN:R09375 R09376]
K14655  
2,5-diamino-6-(5-phospho-D-ribitylamino)-pyrimidin-4(3H)-one deaminase [RN:R09377]
K02858  
3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12] [RN:R07281]
K00794  
6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] [RN:R04457]
K00793  
riboflavin synthase [EC:2.5.1.9] [RN:R00066]
K00861  
riboflavin kinase [EC:2.7.1.26] [RN:R00549]
K00953  
FAD synthetase [EC:2.7.7.2] [RN:R00161]
Class
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
Pathway
map00740  Riboflavin metabolism
map01240  Biosynthesis of cofactors
map01100  Metabolic pathways
Reaction
R00425  
R09375,R09376  
R09377  
R07280  
R07281  
R04457  
R00066  
R00549  
R00161  
Compound
C00044  GTP
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C00199  D-Ribulose 5-phosphate
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C00255  Riboflavin
C00061  FMN
C00016  FAD
Reference
PMID:10940330
  Authors
Bacher A, Eberhardt S, Fischer M, Kis K, Richter G
  Title
Biosynthesis of vitamin b2 (riboflavin).
  Journal
Annu Rev Nutr 20:153-67 (2000)
DOI:10.1146/annurev.nutr.20.1.153
LinkDB

DBGET integrated database retrieval system