KEGG   MODULE: M00922
Entry
M00922            Pathway   Module                                 
Name
CMP-Neu5Ac biosynthesis
Definition
K24257 K01654 K00983
Diagram
M00922

Orthology
K24257  
UDP-N-acetylglucosamine 2-epimerase (hydrolysing) [EC:3.2.1.183] [RN:R00414]
K01654  
N-acetylneuraminate synthase [EC:2.5.1.56] [RN:R01804]
K00983  
N-acylneuraminate cytidylyltransferase [EC:2.7.7.43] [RN:R01117]
Class
Pathway modules; Glycan metabolism; Lipopolysaccharide metabolism
Pathway
map00541  O-Antigen nucleotide sugar biosynthesis
map01250  Biosynthesis of nucleotide sugars
map01100  Metabolic pathways
Reaction
R00414  
R01804  
R01117  
Compound
C00043  UDP-N-acetyl-alpha-D-glucosamine
C00645  N-Acetyl-D-mannosamine
C00270  N-Acetylneuraminate
C00128  CMP-N-acetylneuraminate
Reference
PMID:15629947
  Authors
Feng L, Senchenkova SN, Tao J, Shashkov AS, Liu B, Shevelev SD, Reeves PR, Xu J, Knirel YA, Wang L
  Title
Structural and genetic characterization of enterohemorrhagic Escherichia coli O145 O antigen and development of an O145 serogroup-specific PCR assay.
  Journal
J Bacteriol 187:758-64 (2005)
DOI:10.1128/JB.187.2.758-764.2005
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