KEGG   MODULE: M00943
Entry
M00943            Pathway   Module                                 
Name
Reticuline biosynthesis, dopamine + 4HPAA => (S)-reticuline
Definition
K13382 K13383 K13384 K13385 K13386
Diagram
M00943

Orthology
K13382  
(S)-norcoclaurine synthase [EC:3.5.99.14] [RN:R04305]
K13383  
(RS)-norcoclaurine 6-O-methyltransferase [EC:2.1.1.128] [RN:R05123]
K13384  
(S)-coclaurine-N-methyltransferase [EC:2.1.1.140] [RN:R04692]
K13385  
N-methylcoclaurine 3'-monooxygenase [EC:1.14.14.102] [RN:R05732]
K13386  
3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase [EC:2.1.1.116] [RN:R03832]
Class
Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of phytochemical compounds
Pathway
map00950  Isoquinoline alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R04305  
R05123  
R04692  
R05732  
R03832  
Compound
C03765  4-Hydroxyphenylacetaldehyde
C03758  Dopamine
C06160  (S)-Norcoclaurine
C06161  (S)-Coclaurine
C05176  (S)-N-Methylcoclaurine
C05202  3'-Hydroxy-N-methyl-(S)-coclaurine
C02105  (S)-Reticuline
Reference
PMID:24671624
  Authors
Beaudoin GA, Facchini PJ.
  Title
Benzylisoquinoline alkaloid biosynthesis in opium poppy.
  Journal
Planta 240:19-32 (2014)
DOI:10.1007/s00425-014-2056-8
LinkDB

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