KEGG   REACTION: R05594
Entry
R05594                      Reaction                               
Name
6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase (decyclizing)
Definition
6-Oxocyclohex-1-ene-1-carbonyl-CoA + 2 H2O <=> 3-Hydroxypimeloyl-CoA
Equation
C09821 + 2 C00001 <=> C06714
Comment
two-step reaction (see R10696+R05593)
Reaction class
RC01431  C06714_C09821
Enzyme
3.7.1.21
Pathway
rn00362  Benzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00541  Benzoyl-CoA degradation, benzoyl-CoA => 3-hydroxypimeloyl-CoA
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.7  Acting on carbon-carbon bonds
   3.7.1  In ketonic substances
    3.7.1.21
     R05594  6-Oxocyclohex-1-ene-1-carbonyl-CoA + 2 H2O <=> 3-Hydroxypimeloyl-CoA
Orthology
K07539  6-oxocyclohex-1-ene-carbonyl-CoA hydrolase [EC:3.7.1.21]
Other DBs
RHEA: 39654 40070
LinkDB

KEGG   REACTION: R10696
Entry
R10696                      Reaction                               
Name
6-oxocyclohex-1-ene-1-carbonyl-CoA hydro-lyase (2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA-forming)
Definition
6-Oxocyclohex-1-ene-1-carbonyl-CoA + H2O <=> 2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA
Equation
C09821 + C00001 <=> C09825
Comment
first step of two-step reaction (see R05594, R10696+R05593)
subsequently R05593
Reaction class
RC03237  C09821_C09825
Enzyme
3.7.1.21
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.7  Acting on carbon-carbon bonds
   3.7.1  In ketonic substances
    3.7.1.21
     R10696  6-Oxocyclohex-1-ene-1-carbonyl-CoA + H2O <=> 2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA
Orthology
K07539  6-oxocyclohex-1-ene-carbonyl-CoA hydrolase [EC:3.7.1.21]
Other DBs
RHEA: 40066
LinkDB

KEGG   REACTION: R05593
Entry
R05593                      Reaction                               
Name
2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA hydrolase (decyclizing)
Definition
2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O <=> 3-Hydroxypimeloyl-CoA
Equation
C09825 + C00001 <=> C06714
Comment
second step of two-step reaction (R05594, R10696+R05593)
following after R10696
Reaction class
RC01430  C06714_C09825
Enzyme
3.7.1.21
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.7  Acting on carbon-carbon bonds
   3.7.1  In ketonic substances
    3.7.1.21
     R05593  2-Hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O <=> 3-Hydroxypimeloyl-CoA
Orthology
K07539  6-oxocyclohex-1-ene-carbonyl-CoA hydrolase [EC:3.7.1.21]
LinkDB

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