KEGG   REACTION: R07001
Entry
R07001                      Reaction                               
Name
naphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Definition
Naphthalene + NADPH + Oxygen + H+ <=> (1S,2R)-Naphthalene 1,2-oxide + NADP+ + H2O
Equation
C00829 + C00005 + C00007 + C00080 <=> C14787 + C00006 + C00001
Comment
CYP1A1/2, CYP2B, CYP2E1, CYP2F, CYP2S1, CYP3A4, CYP2A6
Reaction class
RC00001  C00005_C00006
RC01445  C00829_C14787
Enzyme
1.14.14.1       1.14.14.-
Pathway
rn00980  Metabolism of xenobiotics by cytochrome P450
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1
     R07001  Naphthalene + NADPH + Oxygen + H+ <=> (1S,2R)-Naphthalene 1,2-oxide + NADP+ + H2O
    1.14.14.-
     R07001  Naphthalene + NADPH + Oxygen + H+ <=> (1S,2R)-Naphthalene 1,2-oxide + NADP+ + H2O
Orthology
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07409  cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K07412  cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07415  cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K07416  cytochrome P450 family 2 subfamily F [EC:1.14.14.1]
K07420  cytochrome P450 family 2 subfamily S1 [EC:1.14.14.1]
K17683  cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
LinkDB

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