KEGG   REACTION: R08286
Entry
R08286                      Reaction                               
Definition
Ifosfamide <=> Dechloroethylcyclophosphamide + Chloroacetaldehyde
Equation
Comment
CYP2B6, CYP3A4/5
incomplete reaction
Reaction class
RC02225  C06754_C07047
RC02229  C07047_C16550
Enzyme
1.14.14.1       1.14.14.-
Pathway
rn00982  Drug metabolism - cytochrome P450
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1
     R08286  Ifosfamide <=> Dechloroethylcyclophosphamide + Chloroacetaldehyde
    1.14.14.-
     R08286  Ifosfamide <=> Dechloroethylcyclophosphamide + Chloroacetaldehyde
Orthology
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
K17690  cytochrome P450 family 3 subfamily A5 [EC:1.14.14.1]
K17709  cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-]
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