KEGG   REACTION: R08343
Entry
R08343                      Reaction                               
Definition
Citalopram <=> Demethylcitalopram
Equation
Comment
CYP2C19,CYP2D6,CYP3A4: N-demethylation
incomplete reaction
Reaction class
RC00181  C07572_C16608
Enzyme
1.14.14.1       1.14.14.-
Pathway
rn00982  Drug metabolism - cytochrome P450
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1
     R08343  Citalopram <=> Demethylcitalopram
    1.14.14.-
     R08343  Citalopram <=> Demethylcitalopram
Orthology
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
K17712  cytochrome P450 family 2 subfamily D6 [EC:1.14.14.1]
K17721  cytochrome P450 family 2 subfamily C19 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.75 1.14.14.-]
LinkDB

DBGET integrated database retrieval system