KEGG   REACTION: R10105
Entry
R10105                      Reaction                               
Name
4-oxo-4-(pyridin-3-yl)butanal:NADP+ oxidoreductase
Definition
4-Oxo-1-(3-pyridyl)-1-butanone + NADP+ + H2O <=> 3-Succinoylpyridine + NADPH + H+
Equation
C19567 + C00006 + C00001 <=> C19569 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00080  C19567_C19569
Enzyme
1.2.1.83
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn00980  Metabolism of xenobiotics by cytochrome P450
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00811  Nicotine degradation, pyrrolidine pathway, nicotine => succinate semialdehyde
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.83
     R10105  4-Oxo-1-(3-pyridyl)-1-butanone + NADP+ + H2O <=> 3-Succinoylpyridine + NADPH + H+
Orthology
K19700  3-succinoylsemialdehyde-pyridine dehydrogenase [EC:1.2.1.83]
Other DBs
RHEA: 34218
LinkDB

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