KEGG   REACTION: R10954
Entry
R10954                      Reaction                               
Name
tetracenomycin-B2,NADPH:oxygen oxidoreductase (8-demethyltetracenomycin-C-forming)
Definition
Tetracenomycin B2 + 2 Oxygen + H2O + 2 NADPH + 2 H+ <=> 8-Demethyltetracenomycin C + 2 NADP+ + 2 H2O
Equation
C12378 + 2 C00007 + C00001 + 2 C00005 + 2 C00080 <=> C12379 + 2 C00006 + 2 C00001
Reaction class
RC00001  C00005_C00006
RC02681  C12378_C12379
Enzyme
1.14.13.200
Pathway
rn01057  Biosynthesis of type II polyketide products
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00783  Tetracenomycin C/8-demethyltetracenomycin C biosynthesis, tetracenomycin F2 => tetracenomycin C/8-demethyltetracenomycin C
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.200
     R10954  Tetracenomycin B2 + 2 Oxygen + H2O + 2 NADPH + 2 H+ <=> 8-Demethyltetracenomycin C + 2 NADP+ + 2 H2O
Orthology
K15972  tetracenomycin A2 monooxygenase-dioxygenase [EC:1.14.13.200]
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