KEGG   REACTION: R11522
Entry
R11522                      Reaction                               
Name
Fe-coproporphyrin III:hydrogen peroxide oxidoreductase (decarboxylating)
Definition
Fe-coproporphyrin III + 2 Hydrogen peroxide <=> Heme + 2 CO2 + 4 H2O
Equation
C21284 + 2 C00027 <=> C00032 + 2 C00011 + 4 C00001
Comment
two-step reaction (see R12454+R12455)
Reaction class
RC00884  C00032_C21284
Enzyme
1.3.98.5
Pathway
rn00860  Porphyrin metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01240  Biosynthesis of cofactors
Module
M00847  Heme biosynthesis, archaea, siroheme => heme
M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.98  With other, known, physiological acceptors
    1.3.98.5
     R11522  Fe-coproporphyrin III + 2 Hydrogen peroxide <=> Heme + 2 CO2 + 4 H2O
Orthology
K00435  hydrogen peroxide-dependent heme synthase [EC:1.3.98.5]
K25033  hydrogen peroxide-dependent heme synthase [EC:1.3.98.5]
Other DBs
RHEA: 56519
LinkDB

KEGG   REACTION: R12454
Entry
R12454                      Reaction                               
Definition
Fe-coproporphyrin III + Hydrogen peroxide <=> Harderoheme III + CO2 + 2 H2O
Equation
C21284 + C00027 <=> C22173 + C00011 + 2 C00001
Comment
the first step of two-step reaction (see R11522, R12454+R12455)
Reaction class
RC03545  C21284_C22173
Enzyme
1.3.98.5
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.98  With other, known, physiological acceptors
    1.3.98.5
     R12454  Fe-coproporphyrin III + Hydrogen peroxide <=> Harderoheme III + CO2 + 2 H2O
LinkDB

KEGG   REACTION: R12455
Entry
R12455                      Reaction                               
Definition
Harderoheme III + Hydrogen peroxide <=> Heme + CO2 + 2 H2O
Equation
C22173 + C00027 <=> C00032 + C00011 + 2 C00001
Comment
the second step of two-step reaction (see R11522, R12454+R12455)
Reaction class
RC03545  C00032_C22173
Enzyme
1.3.98.5
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.98  With other, known, physiological acceptors
    1.3.98.5
     R12455  Harderoheme III + Hydrogen peroxide <=> Heme + CO2 + 2 H2O
LinkDB

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