Entry |
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Name |
6-(1'-hydroxy-2'-oxopropyl)-tetrahydropterin:NADP+ oxidoreductase
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Definition |
6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin + NADP+ <=> 6-Pyruvoyltetrahydropterin + NADPH + H+
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Equation |
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Comment |
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Reaction class |
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Enzyme |
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Pathway |
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Brite |
Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.153
R11763 6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin + NADP+ <=> 6-Pyruvoyltetrahydropterin + NADPH + H+
1.1.1.213
R11763 6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin + NADP+ <=> 6-Pyruvoyltetrahydropterin + NADPH + H+
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Orthology |
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Reference |
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Authors |
Werner ER, Blau N, Thony B |
Title |
Tetrahydrobiopterin: biochemistry and pathophysiology. |
Journal |
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Reference |
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Authors |
Auerbach G, Herrmann A, Gutlich M, Fischer M, Jacob U, Bacher A, Huber R. |
Title |
The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters. |
Journal |
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LinkDB |
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