REACTION: R12692
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Entry
R12692 Reaction
Name
L-kynurenine:glyoxylate aminotransferase (cyclizing)
Definition
L-Kynurenine + Glyoxylate <=> 4-Hydroxy-2-quinolinecarboxylic acid + Glycine + H2O
Equation
C00328
+
C00048
<=>
C01717
+
C00037
+
C00001
Comment
two-step reaction (see
R01957+R03445
)
Enzyme
2.6.1.63
Brite
Enzymatic reactions [BR:
br08201
]
2. Transferase reactions
2.6 Transferring nitrogenous groups
2.6.1 Transaminases
2.6.1.63
R12692 L-Kynurenine + Glyoxylate <=> 4-Hydroxy-2-quinolinecarboxylic acid + Glycine + H2O
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REACTION: R01957
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Entry
R01957 Reaction
Name
L-kynurenine:glyoxylote aminotransferase (cyclizing)
Definition
L-Kynurenine + Glyoxylate <=> 4-(2-Aminophenyl)-2,4-dioxobutanoate + Glycine
Equation
C00328
+
C00048
<=>
C01252
+
C00037
Comment
the first step of two-step reaction (see
R12692, R01957+R03445
)
Reaction class
RC00006
C00328_C01252
RC00018
C00037_C00048
Enzyme
2.6.1.63
Brite
Enzymatic reactions [BR:
br08201
]
2. Transferase reactions
2.6 Transferring nitrogenous groups
2.6.1 Transaminases
2.6.1.63
R01957 L-Kynurenine + Glyoxylate <=> 4-(2-Aminophenyl)-2,4-dioxobutanoate + Glycine
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Other DBs
RHEA:
19252
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REACTION: R03445
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Entry
R03445 Reaction
Definition
4-(2-Aminophenyl)-2,4-dioxobutanoate <=> 4-Hydroxy-2-quinolinecarboxylic acid + H2O
Equation
C01252
<=>
C01717
+
C00001
Comment
spontaneous
the second step of two-step reaction (see
R12688, R01956+R03445 / R12692, R01957+R03445
)
Reaction class
RC00930
C01252_C01717
Enzyme
2.6.1.7
2.6.1.63
Pathway
rn00380
Tryptophan metabolism
rn01100
Metabolic pathways
Brite
Enzymatic reactions [BR:
br08201
]
2. Transferase reactions
2.6 Transferring nitrogenous groups
2.6.1 Transaminases
2.6.1.7
R03445 4-(2-Aminophenyl)-2,4-dioxobutanoate <=> 4-Hydroxy-2-quinolinecarboxylic acid + H2O
2.6.1.63
R03445 4-(2-Aminophenyl)-2,4-dioxobutanoate <=> 4-Hydroxy-2-quinolinecarboxylic acid + H2O
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Other DBs
RHEA:
42455
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