KEGG   REACTION: R13050
Entry
R13050                      Reaction                               
Name
(S)-lactate:NAD+,ferredoxin oxidoreductase
Definition
(S)-Lactate + 2 NAD+ + 2 Reduced ferredoxin <=> Pyruvate + 2 NADH + 2 Oxidized ferredoxin
Equation
C00186 + 2 C00003 + 2 C00138 <=> C00022 + 2 C00004 + 2 C00139
Reaction class
RC00044  C00022_C00186
Enzyme
1.1.1.436
Pathway
rn00620  Pyruvate metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.436
     R13050  (S)-Lactate + 2 NAD+ + 2 Reduced ferredoxin <=> Pyruvate + 2 NADH + 2 Oxidized ferredoxin
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.1.436
   R11676  Lactate <=> Pyruvate
    R13050  (S)-Lactate <=> Pyruvate
Orthology
K26113  lactate dehydrogenase (NAD+,ferredoxin) subunit LctD [EC:1.1.1.436]
K26114  lactate dehydrogenase (NAD+,ferredoxin) subunit LctC
K26115  lactate dehydrogenase (NAD+,ferredoxin) subunit LctB
Reference
1  [PMID:24762045]
  Authors
Weghoff MC, Bertsch J, Muller V
  Title
A novel mode of lactate metabolism in strictly anaerobic bacteria.
  Journal
Environ Microbiol 17:670-7 (2015)
DOI:10.1111/1462-2920.12493
LinkDB

DBGET integrated database retrieval system