2-oxoadipate dehydrogenase complex: 2-oxoadipate dehydrogenase (see R01940)
TPP-dependent enzymatic reaction (see R13166+R13167)
following after R13166
Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.-
R13167 4-Carboxy-1-hydroxybutyryl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine + Thiamin diphosphate
Nemeria NS, Gerfen G, Nareddy PR, Yang L, Zhang X, Szostak M, Jordan F
Title
The mitochondrial 2-oxoadipate and 2-oxoglutarate dehydrogenase complexes share their E2 and E3 components for their function and both generate reactive oxygen species.