Actinobacillus delphinicola: NCTC12871_00681
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Entry
NCTC12871_00681 CDS
T06572
Symbol
gshAB
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
adp
Actinobacillus delphinicola
Pathway
adp00270
Cysteine and methionine metabolism
adp00480
Glutathione metabolism
adp01100
Metabolic pathways
adp01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
adp00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
NCTC12871_00681 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
NCTC12871_00681 (gshAB)
Enzymes [BR:
adp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
NCTC12871_00681 (gshAB)
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATP-grasp_3
RimK
Dala_Dala_lig_C
GARS_A
ATPgrasp_ST
DEAD
GCS2
Motif
Other DBs
NCBI-ProteinID:
VEJ09236
UniProt:
A0A448TTG9
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Position
1:complement(726128..728401)
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AA seq
757 aa
AA seq
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MNIQLAIKQHQLELLFQQGSYGLEKESVRIWQNGELATTPHPHIFGNRRFHPYIQTDFAE
SQLELITPPNKTVHDTMRWLSAIHQIVLRTLPEDEYIFPFSMPPRLPNESQIQVAKLDNP
ADVAYREHLVEIYGKKKQMVSGIHYNFQISPEFIKQLHQISGQKESLVEFQNALYLKMTR
NFLRYQWILVYLLAATPTVDAAYFRDGSPLKAGQYVRSLRTSRYGYVNEPEVVVSFDSLQ
EYVKTLEHWVSIGKLQAEKEFYSNARLRGANKARDLLASGIQYIEFRLFDLNPFEAYGMS
EEDANFIHYFILLMLWLDEEGTQESVQLGKARLAEVALENPLTETKFKAEGVAMMDKLLA
MLDSLHAPISVKNYAQSKREQFNDPSQTLCAKVVKAIEEVGSYEKLGTELAIKYKAQAME
HFFCLEAFANMELSTQTLMFDAIVKGLKVEILDEQDNFLKLQFAEHIEYVKNGNMTGKDS
YIAPLIMENKVVTKKVLKTAGYNVPDSIEFTDPEVAKASFPLFFDKPMVIKPKSTNFGLG
ISIFQDGVKDKEDFAKAIDIAFREDKSVMVENYLTGTEYRFFVIGDKTLAVLLRVPANVE
GDGEKTIRQLIEIKNDHPLRGDGKRTPLKKIVLGDIELLQLKAQGLTPDSIPAKGEIVQL
RVNSNISSGGDSIDMTDIMHPSYKDIAVGITKALGAAVCGVDLIIPDYTQPATDSIHSWG
VIEANFNPAMLIHIFPHHGTPRRVTRDVLEMLFPEMK
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgaatattcaactagccattaagcaacatcaattagaattgctttttcaacaaggatct
tatgggcttgaaaaagagagtgtacgaatatggcaaaatggtgaattggcaacaacgcct
catccacatatttttggtaatcgtcggtttcatccctatattcaaacagactttgctgaa
agtcagctagaacttattacgccacccaataagacggtgcatgataccatgcgttggctt
tcagcgattcatcaaattgtacttcgtactttacctgaagatgaatatatttttcctttc
agtatgccacctcgcctgcctaatgaaagtcaaatccaggtggctaaattagataatcct
gctgatgttgcttatcgagaacatcttgttgagatttacggtaagaaaaaacagatggtg
agtgggattcattataatttccaaatctcaccagagtttatcaagcaacttcatcaaatt
tcgggacaaaaagagagtcttgttgaatttcagaatgcactttaccttaaaatgacccgt
aattttttacgttatcaatggatattggtgtatttattggcagcgacacctactgtcgat
gctgcctatttccgtgatggctcgccattaaaagcagggcagtacgtacgtagcttacgc
actagccgttatggatatgtgaatgaaccagaagtcgttgtatcttttgatagcttacaa
gagtatgtcaaaacactcgaacattgggtaagtattggtaaattacaggcagaaaaagag
ttttattctaatgcgcgcttgcgtggtgcaaataaagcacgggatctgctcgcatcgggt
atccaatatattgagtttagattattcgatctcaacccatttgaagcttatggtatgagt
gaagaagatgcgaattttattcactattttattcttttaatgctttggcttgatgaagaa
ggcacccaagaaagtgttcagctcggtaaagcacgcctagctgaagttgcgttagaaaat
ccgcttacagaaacaaaatttaaagcggaaggggtggctatgatggataaactattggca
atgctagatagtttacacgccccaatttccgtaaaaaattatgcacaatcaaaacgtgaa
cagtttaatgatccaagccaaaccctttgtgcaaaagttgtgaaagcgattgaagaagtc
ggaagttatgaaaaattaggtaccgaacttgcgattaaatataaagcacaagcgatggag
cattttttctgtttggaagcctttgctaacatggaactttctacccaaactttaatgttt
gatgcaattgttaaagggctaaaagttgagattctagatgagcaggataatttcttaaaa
ttgcaatttgctgagcatattgaatatgtgaaaaacggcaatatgacgggaaaagatagt
tatattgcaccgcttatcatggaaaacaaagtggtaacgaagaaggtattaaaaaccgca
ggctataacgttccagatagtattgagtttactgatcccgaagtggcaaaggcaagtttc
ccattgttttttgataaacctatggtgattaaaccaaaatcaacgaacttcggtttggga
atcagtattttccaagatggcgtaaaagataaagaagattttgcgaaagccatagatatt
gcctttagagaagataaatccgttatggtagagaattatcttactggaacggaatatcgt
ttctttgtgattggtgataaaacattagcggttttattgcgtgttcccgctaacgtagaa
ggggacggtgaaaaaacgattcgccaacttattgaaattaaaaatgatcatcctcttcgt
ggtgatggcaaacgaactccattgaaaaaaattgtgttgggcgatattgaattattacaa
ttaaaagcacaaggattaacgcctgatagtatccctgcgaaaggtgaaattgtacaactg
cgtgtaaattctaatattagctcaggtggcgatagtattgatatgacggatattatgcat
ccaagttataaagatatcgcagtgggcattacaaaagcattgggtgcggcagtttgtggg
gttgatttgattattccagattatactcaacctgccacggatagtatccattcctggggc
gtaattgaagcgaattttaatcccgcaatgcttattcatattttcccacatcacggcacc
ccacgacgagtgacgagagatgtattggaaatgcttttcccagaaatgaaatag
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