Entry
Symbol
gshA
Name
glutamate--cysteine ligase [EC:
6.3.2.2 ]
Pathway
map00270 Cysteine and methionine metabolism
Module
M00118 Glutathione biosynthesis, glutamate => glutathione
Reaction
R00894 L-glutamate:L-cysteine gamma-ligase (ADP-forming)
R10993 L-glutamate:2-aminobutanoate gamma-ligase (ADP-forming)
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
K01919 gshA; glutamate--cysteine ligase
09106 Metabolism of other amino acids
00480 Glutathione metabolism
K01919 gshA; glutamate--cysteine ligase
Enzymes [BR:ko01000 ]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
K01919 gshA; glutamate--cysteine ligase
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Reference
Authors
Jez JM, Cahoon RE, Chen S
Title
Arabidopsis thaliana glutamate-cysteine ligase: functional properties, kinetic mechanism, and regulation of activity.
Journal
Sequence
Reference
Authors
Harth G, Maslesa-Galic S, Tullius MV, Horwitz MA
Title
All four Mycobacterium tuberculosis glnA genes encode glutamine synthetase activities but only GlnA1 is abundantly expressed and essential for bacterial homeostasis.
Journal
Sequence
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