Shigella flexneri NCTC1 (serotype 2a): NCTC1_02986
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Entry
NCTC1_02986 CDS
T03751
Symbol
gshA
Name
(GenBank) glutamate--cysteine ligase,Glutamate--cysteine ligase,glutamate--cysteine ligase,glutamate--cysteine ligase,Glutamate-cysteine ligase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
sft
Shigella flexneri NCTC1 (serotype 2a)
Pathway
sft00270
Cysteine and methionine metabolism
sft00480
Glutathione metabolism
sft01100
Metabolic pathways
sft01240
Biosynthesis of cofactors
Module
sft_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
sft00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
NCTC1_02986 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
NCTC1_02986 (gshA)
Enzymes [BR:
sft01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
NCTC1_02986 (gshA)
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Motif
Pfam:
Glu_cys_ligase
Motif
Other DBs
NCBI-ProteinID:
CDX08135
UniProt:
Q7UBU4
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All DBs
Position
1:complement(2751695..2753251)
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AA seq
518 aa
AA seq
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MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTD
FAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYG
TSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGY
FRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLG
YTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELY
APIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALA
DAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLLQVGKDLFRDLKRVAQTL
DSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPL
EILREEDFVAEREASERRQQEMETADTEPFAVWLEKHA
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
ttgatcccggacgtatcacaggcgctggcctggctggaaaaacatcctcaggcgttaaag
gggatacagcgtgggctggagcgcgaaactttgcgtgttaatgctgatggcacactggca
acaacaggtcatcctgaagcattaggttccgcactgacgcacaaatggattactaccgat
tttgcggaagcattgctggaattcattacaccagtggatggtgatattgaacatatgctg
acctttatgcgcgatctgcatcgttatacggcgcgcaatatgggcgatgagcggatgtgg
ccgttaagtatgccatgctacatcgcagaaggtcaggacatcgaactggcacagtacggc
acttctaacaccggacgctttaaaacgctgtatcgtgaagggctgaaaaatcgctacggc
gcgctgatgcaaaccatttccggcgtgcactacaatttctctttgccaatggcattctgg
caagcgaagtgcggtgatatctcgggcgctgatgccaaagagaaaatttctgcgggctat
ttccgcgttatccgcaattactatcgtttcggttgggttattccttatctgtttggtgca
tctccggcgatttgttcttctttcctgcaaggaaaaccaacgtcgctgccgtttgagaaa
accgagtgcggtatgtattacctgccgtatgcgacctctcttcgtttgagcgatctcggc
tataccaataaatcgcaaagcaatcttggtattaccttcaacgatctttacgagtacgta
gcgggccttaaacaggcaatcaaaacgccatcggaagagtacgcgaagattggtattgag
aaagacggtaagaggctgcaaatcaatagcaacgtgctgcagattgaaaacgaactgtat
gcgccgattcgtccaaaacgcgttacccgcagcggcgagtcaccttctgatgcgctgtta
cgtggcggcattgaatatattgaagtgcgttcgctggacatcaacccgttctcgccgatt
ggtgtagatgaacagcaggtgcgattcctcgacctgtttatggtctggtgtgcgctggct
gatgcaccggaaatgagcagtagcgaacttgcctgtacgcgcgttaactggaaccgggtg
atccttgaaggtcgcaaaccgggcctgacgctgggtatcggctgcgaaaccgcgcagttc
ccgttactgcaggtgggtaaagatctgttccgcgatctgaaacgcgtcgcgcaaacgctg
gatagcattaacggcggcgaagcgtatcagaaagtgtgtgatgaactggttgcctgcttc
gataatcccgatctgactttctctgcccgtatcttaaggtctatgattgatactggtatt
ggcggaacaggcaaagcgtttgcagaagcctaccgtaatctgctgcgtgaagagccgctg
gaaattctgcgcgaagaggattttgtagccgagcgcgaggcatctgaacgccgtcagcag
gaaatggaaaccgctgataccgaaccgtttgcggtgtggctggaaaaacacgcctga
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