Salmonella enterica subsp. enterica serovar Typhi Ty2: t2715
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Entry
t2715 CDS
T00121
Symbol
gshA
Name
(GenBank) gamma-glutamylcysteine synthetase
KO
K01919
glutamate---cysteine ligase [EC:
6.3.2.2
]
Organism
stt
Salmonella enterica subsp. enterica serovar Typhi Ty2
Pathway
stt00270
Cysteine and methionine metabolism
stt00340
Histidine metabolism
stt00480
Glutathione metabolism
stt01100
Metabolic pathways
stt01110
Biosynthesis of secondary metabolites
stt01240
Biosynthesis of cofactors
Module
stt_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
stt00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
t2715 (gshA)
00340 Histidine metabolism
t2715 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
t2715 (gshA)
Enzymes [BR:
stt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
t2715 (gshA)
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Paralog
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Motif
Pfam:
Glu_cys_ligase
Motif
Other DBs
NCBI-ProteinID:
AAO70281
UniProt:
Q8Z4D6
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All DBs
Position
complement(2805687..2807243)
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AA seq
518 aa
AA seq
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MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTVHPEALGSALTHKWITTD
FAEALLEFITPVDGDIQHMLTFMRDLHRYTARKLGDERMWPLSMPCYIAEGQDIELAQYG
TSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGVTEGEAAKEKISAGY
FRLIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPFEKTDCGMYYLPYATSLRLSDLG
YTNKSQSNLGITFNDLHEYVAGLKRAIKTPSEEYARIGVEKDGKRLQINSNVLQIENELY
APIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCVLA
DAPEMSSDELLCTRTNWNRVILEGRKPGLTLGIGCETAQFPLPKVGKDLFRDLKRVAQTL
DSIHGGEEYQKVCDELVACFDNPELTFSARILRSMIDEGIGGTGKAFGEAYRNLLREEPL
EILQEEEFIAERDASVRRQQEIEAADTEPFAAWLAKHA
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
ttgatcccggacgtatcacaggctctggcctggctggaaaaacatcctcaggcgttaaag
gggatacagcgcgggttagagcgcgaaacgctgcgtgtcaatgctgatggcacgctggcg
acaacagttcatcctgaagcgttaggttcagcgctgacccataaatggattaccacagat
tttgcggaagccctactggagtttattacgccagtcgatggcgatatccagcatatgctc
acctttatgcgcgatctccatcggtatacggccaggaaactgggcgatgagcggatgtgg
ccattaagtatgccctgctatattgcggaagggcaggacatagagctggcgcagtacggc
acatcaaataccgggcgctttaagacgctctatcgcgaagggctgaaaaatcgttatggc
gctttgatgcaaaccatttccggcgtacattacaatttttcattaccgatggcgttctgg
caggcgaaatgcggcgttacggaaggcgaagcggcaaaagaaaaaatttctgccggctat
tttcgtctgattcgcaactattaccgttttggctgggtcatcccctatctgtttggcgcg
tctccggccatttgttcctctttcctgcaagggaagccaaccacattaccgtttgaaaaa
acggactgcggcatgtactacctgccatatgcgacgtcgctgcgtttgagtgatttgggc
tataccaataagtcgcaaagcaatctgggtattacgtttaacgatctacatgaatacgtt
gcaggtctgaaacgggcgattaaaacgccgtcagaagagtacgcgcggattggtgtggaa
aaagacggtaagcggctacagattaacagcaacgttctgcaaattgaaaatgagctgtac
gcgcccattcgtcccaagcgcgtgacgcgcagcggcgaatcgccttcagatgcgcttctg
cgtggtggtattgagtacatcgaagttcgttctctcgatattaatccgttctcaccgatc
ggcgtagacgagcaacaggtgcgcttcctcgatctgtttatggtctggtgcgtattggcc
gatgcgccggaaatgagtagcgatgagctgttatgtacgcgtactaactggaatcgcgtt
attctggaagggcgtaagccgggccttaccctggggattggctgtgaaaccgcgcagttc
ccgctgcctaaagtagggaaagatctcttccgcgatctgaaacgcgtggcgcaaacgctg
gacagtatccacgggggagaggagtatcaaaaggtgtgtgatgagttggtcgcctgcttt
gataatcctgaactgacattctctgcccgaatcttacggtctatgattgatgaaggcatt
ggcggcactgggaaagcgttcggtgaggcttaccgtaatctgttacgcgaagagccgctg
gagattttacaggaagaagagtttattgctgaacgtgacgcttcagtacgtcgtcagcag
gagattgaggcggcggataccgagccgtttgccgcgtggcttgcgaaacacgcctga
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