Lacticaseibacillus rhamnosus ATCC 8530: LRHK_1206
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Entry
LRHK_1206 CDS
T01961
Symbol
gshAB
Name
(GenBank) glutamate--cysteine ligase/gamma-glutamylcysteine synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
lra
Lacticaseibacillus rhamnosus ATCC 8530
Pathway
lra00270
Cysteine and methionine metabolism
lra00480
Glutathione metabolism
lra01100
Metabolic pathways
lra01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
lra00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
LRHK_1206 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
LRHK_1206 (gshAB)
Enzymes [BR:
lra01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
LRHK_1206 (gshAB)
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Motif
Pfam:
ATP-grasp_6
GARS_A
Motif
Other DBs
NCBI-ProteinID:
AER63992
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Position
1140575..1142536
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AA seq
653 aa
AA seq
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MNHYWQLIRKEHLFGLAAQTRMGVIRTVKPILPAETNLPQWPQRSRHALVQPLSASVLQI
VTPLLDDFPAVIDQLRAGLSRIWTALPEAGHLSAFTAEKVNQQTVRIVLPETLFERLYTA
ENFQGHGPEYVAYRNEVYQLVADGLTRQLPLLTYLFSASPADGHRAFWPSPDQERQLVQK
VTDPDHLDRILALDVVVELDPYAASGITTQMLTFLRDSCWFALSQPAIPVAAASEVRRHA
VMQARTIAQMAPDAKVAELPAMLDAMATWLNHVGIDAQQKQAFELMQTRLVKPETSLASQ
VLATFHDQTAADESLSRQAQADLTSTNELPGMTDLSENTQTLLQAAMDGGYQFTILDRQQ
NLVQIATDTQTQVIADGVVTNYTPANAMIVATHRHTAKQLLAAAGIPVARGAKFTKWPDA
KAAFEHSFAHKSIVVKPEARSQGEAVEQFSIPPTEKQFDRAFHEANRHHGVLIEMMARGT
TYHFTIIGQQVLSVLETAAANVVGDGRKAIKELIALKNGHRATSRQLQLDASARRQLKAQ
ALTPETVLQRGQQVFLTTAAHPQTGGDLYDVTDEIDDSYKQLALKAAATLDLPVAAVDIV
IDNLYAPYDPEADGQANVISVNPVPDLAAPLHLDMGESRALAPALLNWLFAVR
NT seq
1962 nt
NT seq
+upstream
nt +downstream
nt
gtgaatcattattggcaactgattcgaaaagaacatttgtttggcttggccgctcagacg
cgaatgggtgtgattcgaactgtcaaacccattctgccggcagaaaccaacttaccgcag
tggccgcaacgtagccgccatgctttggttcagccactttctgcttcagtgttgcaaatc
gtaaccccattactagacgattttcctgccgttattgaccagttacgggctgggctaagt
cgaatttggacggcattaccggaagcagggcacttatcggcttttaccgcggaaaaagtg
aaccagcaaacggtccggatagttttaccggaaacactatttgaacggttgtacacagca
gagaattttcagggccatggtccggaatatgttgcctatcgtaatgaagtttatcagttg
gtagcagacgggttaacgcggcagttgccattgttgacttacttgttttctgcttctcca
gctgacggtcaccgcgcattttggccgtcaccggatcaggaacggcaactggttcaaaaa
gtgacggatccagaccacttggatcgaattcttgcgctggacgttgtggtggagcttgat
ccgtacgctgctagcgggatcacgacccaaatgctgacattcttgcgtgatagctgctgg
tttgcgctaagtcaaccggccattccggttgccgcggcaagtgaagtacgccggcatgct
gtcatgcaggcgcggacaattgcccagatggcacctgatgccaaagtcgccgagctgccg
gcaatgctggatgcgatggcgacatggttaaatcatgttggcattgatgcgcaacaaaaa
caagcttttgaattgatgcagacgcgattagtgaagccggaaacgagccttgccagtcaa
gttcttgcaacgtttcatgaccaaacagctgcggatgagtcattgagtcggcaagcacag
gcggacttaaccagtaccaatgagttgccggggatgacagatttatcggaaaacacccag
acattgttacaagctgctatggatggggggtatcagttcacgatactggatcgtcaacag
aatctggtgcaaattgccacggatacccagacacaagtcattgcagacggcgttgttacc
aactatacgccagccaatgccatgatcgttgccacccatcggcacacagccaaacagttg
ctggccgcagcaggaataccagttgcacgtggggctaagtttactaaatggccggatgcc
aaagcagcttttgagcacagctttgcgcataaaagtattgtggtgaaacccgaggcacgc
agccaaggcgaagcggttgagcagttttcgataccaccgactgaaaagcagtttgaccga
gcctttcatgaagccaatcgccatcatggggtgctcattgaaatgatggcacgcggcacg
acctaccattttaccatcatcgggcaacaagtgctcagcgttttggaaacagcagcagct
aatgttgtaggcgatgggcgcaaagccattaaggaattgatcgccttgaaaaatggtcac
cgcgcgacttcccggcaattgcagcttgatgctagcgcgcgccgtcagttaaaggcacaa
gcgttgacacctgagactgtgcttcaacgcgggcagcaggttttcttaaccactgccgcg
catccgcaaaccggtggcgatttgtatgacgtgacggacgagattgatgacagttacaag
caactggcgctaaaagctgccgccacacttgatttgccggtagcagctgtcgacattgtg
attgataatctgtatgcaccatatgatccggaggcagatgggcaggcgaacgtaattagt
gtcaatccggtaccggatctcgctgcgcctttgcacctggacatgggcgaatcacgcgca
cttgccccggcattgctaaactggctgtttgctgtgagataa
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