Pradoshia sp. D12: F7984_01100
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Entry
F7984_01100 CDS
T06218
Symbol
gshAB
Name
(GenBank) bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
prd
Pradoshia sp. D12
Pathway
prd00270
Cysteine and methionine metabolism
prd00480
Glutathione metabolism
prd01100
Metabolic pathways
prd01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
prd00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
F7984_01100 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
F7984_01100 (gshAB)
Enzymes [BR:
prd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
F7984_01100 (gshAB)
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GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATPgrasp_ST
ATP-grasp_3
Dala_Dala_lig_C
GARS_A
Motif
Other DBs
NCBI-ProteinID:
QFK69971
UniProt:
A0A5J6XLA1
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Position
192399..194633
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AA seq
744 aa
AA seq
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MTNIDHRLLKLMKEKHLSETLFRGNFGLEKENNRVHKNGTLALTPHPSSFGDRAKHPYIT
TDFSESQIEMVTPVFPTIDEAFEFLENIHDIVSLELSKQGEYLWPGSNPPILPDECLIPI
AKLENDQETEYRYKLAQKYGRKKQLISGIHYNFSFSDELLHVLYDEQSSHKTYKEFKNDI
YLKISRNFNRYRDLLVDVTGASPVFHNTYNQDCVLRAEQLNQGSYYLPQVHSFRNSVCGY
KNRKDYQVSYQSVEEYVEDIHNLIQKHELLSAKEYYHTLRLKAGAGEDPLQGLLDKGIQY
IEIRLLDLNPLFKIGTSKENLYFIHLFILYMLLLEEEEKTDLNYLSIIAEMKEMARELSL
ADKYIHILVEVENMLIDPELSYAARIKEGIKQSSYELFHMKHSFDYLHESEKHSFTLLGY
EDMELSTQILIKDAIKRGIGIEIVDRDENFIALSDGKKTEYVKQATKTSLDSYSTVLVME
NKLVTKKILRNAGMRVPNGGAYQSLEEAVMDYEKYKAKQIVIKPKSTNFGLGITIFKDSF
SKEDYEKALGMAFLHDRTVLVEEFLSGKEYRFLVMGDEVTGILHRVPANVKGDGQSSIAE
LVTAKNKDPLRGKGYKTPLEKIQLGESEALFLKGQGKDFDYIPAEGELVYLRENSNISTG
GDSLDLTDAISGSYKELAIQAAKAAGATICGVDMMIDDPTANVSEQNYGIIELNFNPAIH
IHCYPYKGENRRAGERILQLLFGK
NT seq
2235 nt
NT seq
+upstream
nt +downstream
nt
atgacaaatatagaccatagacttctaaagctcatgaaagaaaaacacctatcggaaaca
ttgtttaggggaaattttggccttgaaaaagaaaataatagggttcataaaaatgggaca
ttagctttaacaccacacccgtcttcattcggtgacagagcaaagcacccgtacattaca
accgacttttctgagtctcagatagagatggtgactccggtgttcccgacgattgatgag
gcgtttgagtttctggaaaatatacatgatattgtgagtttagaattatctaagcaagga
gaatacttatggccaggcagtaatcctcctattcttcccgatgaatgcttgattccaatc
gccaagctggaaaacgatcaggagaccgagtaccgatataaacttgcacagaaatacgga
agaaaaaagcaattaataagcggtatccattacaatttctcgttctctgacgaactattg
cacgtattgtatgatgaacaatccagccataaaacatataaagagtttaaaaatgatatt
tatttaaaaatcagccgtaattttaaccgctatcgagatttattggttgatgtgactggg
gccagtccagtgtttcataatacttataaccaagactgcgtcttaagggcagagcaatta
aatcaaggaagttattatctccctcaagttcattcatttagaaacagcgtatgtggttat
aaaaatcgaaaggactaccaggtttcctatcaatcagttgaagaatatgttgaggatatt
cacaatttgattcagaaacatgaattgttgagcgcaaaagaatattatcatacgctccgc
ttgaaggcaggtgctggtgaagatcccctgcaaggtcttttagataaagggattcaatat
attgagattcggttgttagatttgaaccctctgtttaaaatcggtacaagtaaagagaat
ctctatttcattcacttatttattttgtatatgcttctgcttgaagaagaggaaaagacc
gatttgaattatttatccatcatagctgaaatgaaggaaatggcacgagaattatctcta
gctgataaatacatccatatactggtcgaagttgaaaatatgctaattgatccggaactc
tcttatgcagcaagaataaaggaaggtataaagcagtcatcctacgaattgtttcatatg
aaacattcttttgattatttacacgaaagtgaaaaacattcattcactttattgggatat
gaggatatggagctttcaacgcaaattttaattaaagatgctattaaaagaggaatagga
atcgagattgttgatcgagatgaaaactttattgctttatctgatgggaagaaaacagag
tatgtgaagcaggcgaccaaaacatcgctcgattcatacagtactgttttggttatggag
aataagcttgttacgaagaagattcttcgaaatgctgggatgagagttccgaatggaggg
gcttatcaatctctagaggaagcagttatggattatgagaaatataaggccaagcaaatt
gtaatcaagccgaaatcaacaaattttggtttgggaattacgattttcaaagattcattt
tcaaaagaggactatgaaaaagcattagggatggcttttcttcatgatcgtactgtgttg
gttgaggaattcctcagtggaaaggaatatcggtttcttgtaatgggagatgaagtgaca
gggatccttcatcgtgtcccagccaatgtgaaaggtgatggacaatccagtattgctgaa
ttggttacagcgaaaaataaagatcctttacggggaaagggctataaaacacccttggag
aagattcagttaggggaaagtgaagcacttttcctaaagggacagggaaaggatttcgat
tatatcccggcggaaggagagcttgtttatttaagagagaattctaatatcagcactggc
ggggatagtctagatcttactgatgctatatcagggagctataaggaattggccattcaa
gctgcaaaagctgctggtgctacaatctgtggagtcgatatgatgattgatgatccgact
gccaatgtcagtgaacaaaattatggaattatcgaacttaattttaatcctgcgatccat
attcattgttatccttacaaaggagaaaatagaagagcaggggagcgaattcttcaatta
ctttttgggaagtaa
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