Streptomyces tirandamycinicus: DDW44_28490
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Entry
DDW44_28490 CDS
T06843
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
stir
Streptomyces tirandamycinicus
Pathway
stir00270
Cysteine and methionine metabolism
stir00480
Glutathione metabolism
stir01100
Metabolic pathways
stir01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
stir00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
DDW44_28490 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
DDW44_28490 (egtA)
Enzymes [BR:
stir01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
DDW44_28490 (egtA)
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GFIT
Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
AWI32293
UniProt:
A0A2S1T0U7
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Position
complement(6593373..6594641)
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AA seq
422 aa
AA seq
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MAAPGRAGSAPPLSEDDAEELLRCICFKTGPPRTVGVELEWLVHDRHLPHLPVDEARLDR
AFAGLRGLALGSALTFEPGGQLELSSPPAASLMECIDSTTADLAAVRTALARSGLVLTGC
GHDPWNPPRRLLREPRYDAMEACLDRTGPAGRSMMCSTASVQVCLDAGYEEPGPLGLGRR
WQLAHLLGAVLVAAFANSPAGAGGETGWRSTRQALWADLDPARALAPPPGAPPRDAWAAH
VLDTPVMCVRAAQGPWPVPEGLTFREWIRSGKPRPPTRADLDYHMTTLFPPVRPRGHLEL
RMIDAQPGETGWMVPLAVTTALFDDPEAAETAYRTVKPLAETAGPLPAPRNPLWVGAARH
GLSDPELHGAAVGCFAVALEALPRLGASKAVQDAVAAFHERHVLPGRCPADDFPLLSKET
RS
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atggcagcaccgggccgcgcgggcagtgccccgccgctctccgaggacgacgccgaggaa
ctgctccgatgtatctgcttcaagacgggcccgccccgcaccgtcggagtggagctggaa
tggcttgtgcacgaccggcatctgccgcacctgcccgtcgacgaggcccgtctcgaccgg
gcattcgccggactgcggggcctggccctcggttcggcgctcaccttcgaaccgggcggg
cagctggagctcagctcgccgcccgccgcgtcgctgatggagtgcatcgactccaccacg
gccgatcttgccgccgtgcggaccgcgctggcccgctccgggctggtgctcaccgggtgc
ggccacgacccctggaacccgccgcgccggctgctgcgcgaaccccggtacgacgccatg
gaggcgtgcctggaccgcaccggccccgccgggcggtccatgatgtgctccaccgcgtcc
gtgcaggtgtgcctggacgccgggtacgaggagccgggtccgctgggcctcggccgccgc
tggcagctggcgcacctgctgggggccgtgctcgtcgccgccttcgccaactcgccggcc
ggagcgggcggggagaccggctggcgctcgacccggcaggcgctgtgggccgatctggac
ccggcgcgggccctggcaccgcccccgggggcaccaccccgtgacgcctgggcggcgcat
gtgctggacacgccggtgatgtgcgtccgtgccgcccagggtccgtggccggtaccggag
gggctgaccttccgggagtggatccggtccgggaagccccggccgcccacccgcgccgac
ctcgactaccacatgaccacgctgttcccgccggtgcggccgcgcgggcacctcgaactg
cgcatgatcgacgcgcagccgggagagacgggctggatggtcccgctcgccgtcaccacg
gccctcttcgacgacccggaggccgccgagaccgcctaccgcacggtcaagccgctcgcc
gagaccgccggcccgctgcccgcgccccgcaacccgctgtgggtgggcgccgcacggcac
ggcctgtccgaccccgagctgcacggcgccgcagtcggctgcttcgccgtcgccctggag
gccctcccccggctgggcgcctcgaaggccgtacaggacgcggtcgccgcgttccacgag
cgccatgtactgcccggccggtgcccggccgacgacttcccgctcctcagcaaggagacc
cgctcatga
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