Escherichia coli O127 H6 E2348/69 (EPEC): E2348C_2956
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Entry
E2348C_2956 CDS
T00796
Symbol
gshA
Name
(GenBank) gamma-glutamate-cysteine ligase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
ecg
Escherichia coli O127:H6 E2348/69 (EPEC)
Pathway
ecg00270
Cysteine and methionine metabolism
ecg00480
Glutathione metabolism
ecg01100
Metabolic pathways
ecg01240
Biosynthesis of cofactors
Module
ecg_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ecg00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
E2348C_2956 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
E2348C_2956 (gshA)
Enzymes [BR:
ecg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
E2348C_2956 (gshA)
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Paralog
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GFIT
Motif
Pfam:
Glu_cys_ligase
Motif
Other DBs
NCBI-ProteinID:
CAS10504
UniProt:
B7UHB1
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All DBs
Position
complement(3047210..3048766)
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AA seq
518 aa
AA seq
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MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTD
FAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYG
TSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGY
FRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLG
YTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELY
APIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALA
DAPEMSSKELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTL
DSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPL
EILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
ttgatcccggacgtatcacaggcgctggcctggctggaaaaacatcctcaggcgttaaag
gggatacagcgtgggctggagcgcgaaactttgcgtgttaatgctgatggcacactggca
acaacaggtcatcctgaagcattaggttctgcactgacccataaatggattactaccgat
tttgcggaagcattgctggaattcattacaccagtggatggtgatattgaacatatgctg
acctttatgcgcgatctgcatcgctatacggcgcgcaatatgggcgatgagcggatgtgg
ccgttaagtatgccatgctatatcgcagaaggtcaggacatcgaactggcacagtacggc
acttctaacaccggtcgctttaaaacgctgtaccgtgaagggctgaaaaatcgctacggc
gcgctgatgcaaaccatttccggcgtgcactataatttctctttgccaatggcattctgg
caagcgaagtgcggtgatatctcgggcgctgatgccaaagagaaaatttctgcgggctat
ttccgcgttatccgcaattactatcgtttcggttgggtcattccttatctgtttggtgcg
tctccagcgatttgttcttctttcttgcaaggaaaaccaacgtcgctgccgtttgagaaa
accgagtgcggtatgtattacctgccgtatgcgacctctcttcgtttgagcgatcttggc
tataccaataaatcgcaaagcaatcttggtatcaccttcaatgatctctacgagtacgtg
gcgggccttaaacaggcaatcaaaacgccatcggaagagtacgcgaagattggtattgag
aaagacggtaagcggctgcaaatcaacagcaatgtgctgcagattgaaaacgaactgtac
gcgccgattcgtccaaaacgcgttacccgcagcggcgagtcgccttctgatgcgctgtta
cgtggcggcattgaatatattgaagtccgctcgctggatatcaacccattctcgccgatt
ggtgtagatgaacagcaggtgcgattcctcgacctgtttatggtctggtgtgcgctggct
gatgcaccggaaatgagcagtaaagaacttgcctgtacacgcgttaactggaaccgggtg
atcctcgaaggtcgcaaaccgggcctgacgctgggtatcggctgcgaaaccgcgcagttc
ccgttaccgcaggtgggtaaagatctgttccgcgatctgaaacgcgttgcgcaaacgctg
gatagcattaacggcggcgaagcgtatcagaaagtgtgtgatgaactggtcgcctgcttc
gataatcccgatctgactttctctgcccgtatcttaaggtctatgattgatactggtatt
ggcggaacaggcaaagcgtttgctgaagcgtaccgtaatctgctgcgtgaagagccgctg
gaaattctgcgcgaagaggattttgtcgccgagcgcgaggcgtctgaacgccgtcagcag
gaaatggaagccgctgataccgaaccgtttgcggtgtggctggaaaaacacgcctga
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