Actinobacillus lignieresii: NCTC10568_01805
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Entry
NCTC10568_01805 CDS
T06678
Symbol
gshA
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
alig
Actinobacillus lignieresii
Pathway
alig00270
Cysteine and methionine metabolism
alig00480
Glutathione metabolism
alig01100
Metabolic pathways
alig01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
alig00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
NCTC10568_01805 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
NCTC10568_01805 (gshA)
Enzymes [BR:
alig01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
NCTC10568_01805 (gshA)
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATP-grasp_3
ATPgrasp_ST
GARS_A
Dala_Dala_lig_C
Motif
Other DBs
NCBI-ProteinID:
VEB27041
LinkDB
All DBs
Position
1:1774841..1777114
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AA seq
757 aa
AA seq
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MKLQQLIKTHHLGLLFQQGKFGIEKESQRIDNKGNIVTTAHPSVFGNRSYHPYIQTDFAE
SQLELITPPNDKLEDTYRWLSAIHEVTLRSLPDDEYIFPFSMPAGLPPESEIKEAQLDNE
WDVKYREHLSAIYGKYKQMVSGIHYNFQISEEFVESAFALQTEYCDKIAFRNALYMKLAN
NFLRYQWILVYLLAATPTVEAQYFGKNSPLAEGQLVRSLRSGPYGYVNAPHVVINHDSLQ
QYVESLEHFVATGDLLAEKEFYSNVRLRGAKKARELLKKGVKYAEFRLFDLNPLSPYGIE
LADAKFIHLFLLAMLWIDETSGQKEVELGTQKLYQVALEDPRSHTAFQAEGEAILNLMLA
MLDDLSVPQNEKDLLQQKLAQFADPSQTVNGRLLAAIEQAGSYKALGAQLAQQYKAQAFE
RFYAISAFDNMELSTQALLFDAIQQGLQIELLDENDQFLALKFGDHLEYVKNGNMTSHDQ
YISPLIMENKVVTKKVLAKAGFNVPKSIEFTSLEQAVAHYPLFEGKAVVIKPKSTNYGLG
ITIFQQGVTDKADFAKAIEIAFREDKEVMVEDYLVGTEYRFFVLGDETLAVLLRVPANVK
GDGAHTVRELVEAKNSDPLRGDGSRSPLKKIALGDIELLQLKEQGLTPDSIPADGQIVQL
RANSNISTGGDSIDMTDQMHDSYKQLAVGIAKAMGAKVCGVDLIIPDLTKAAEPSLRSWG
VIEANFNPMMMMHIFPYQGKSRRLTKAVLKMLFPGLP
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgaaattacaacaactgattaaaactcatcaccttggtttactgtttcaacaaggtaaa
tttggtatcgaaaaagaaagccaacgcattgataataaagggaatattgttactaccgcc
catcctagcgtttttggtaaccgcagttatcatccctatattcaaaccgattttgcagaa
agtcagttagaacttatcacaccgccaaacgataaattggaagacacatatcgttggcta
tcggctattcacgaggtaacgttacgttcgttgcccgatgatgaatatattttcccattc
agtatgcctgccggtttaccgccggaatccgaaatcaaagaagcacaattagataacgaa
tgggacgtgaaatatcgtgaacatctttccgccatttatggcaaatacaagcaaatggtg
agcggtattcactataatttccaaatttccgaagaatttgtcgaaagcgcatttgcatta
caaacggaatactgcgataaaattgcgttccgcaatgcgctatatatgaaattagccaat
aactttttacgttatcaatggattttagtttatttgcttgccgcaaccccaactgtagaa
gcgcaatatttcggtaaaaactcaccgcttgcagaagggcaattagtacgtagtttacgt
tccggcccgtatggctatgtcaatgcccctcatgtggtgatcaatcatgatagcctacaa
caatatgtcgaatcgctagaacattttgtagcaaccggcgatttgttggcagaaaaagaa
ttctattcgaacgtacgtttacgcggtgcgaaaaaagcacgtgaattgcttaagaaaggg
gttaaatatgcggaattccgtttatttgatctcaatccgctttcaccttacggtattgaa
cttgccgatgccaaatttattcatctattcttacttgcgatgttatggatagatgaaaca
agcggtcaaaaagaagtcgaacttggcacacaaaaactataccaagttgcacttgaagat
cctcgttcgcacactgcgttccaagcagagggagaagcgatccttaatctgatgctggca
atgctggacgatctttctgtaccacaaaacgagaaagatttattacaacaaaaactggca
caatttgctgatccgagccaaacggtaaacggtcgtttattagccgcaatcgaacaagcc
ggcagctataaagcactcggtgcacaacttgctcaacaatataaagcgcaagcattcgag
cgtttttatgcgatttccgcgttcgataatatggagctttctacacaggccttattattt
gatgcgatccaacagggattacagatcgaattgcttgatgaaaacgatcagttcctcgca
ctcaaattcggtgatcatctcgaatatgtgaaaaatggcaatatgaccagtcacgatcag
tacatttcgccattaattatggaaaataaagtcgtaaccaaaaaagtattagctaaagcc
ggttttaacgtaccgaaaagtattgaatttacctcgctagaacaagcggtggcacactat
ccgttatttgaaggtaaagcggtggtaattaagccgaaatcgaccaattacggtttaggc
attacgattttccaacaaggcgtgacggataaagccgattttgccaaagcgattgaaatt
gccttccgtgaagataaagaagtgatggtggaagactatttagtcggtaccgaatatcgt
ttctttgtgctaggcgatgaaactctagcggtattgttgcgtgtgccggcgaatgtaaaa
ggtgatggcgcacatacggtgcgtgaattggtggaagcgaaaaacagtgatccgctacga
ggtgacggctctcgttcaccattgaagaaaatcgccctcggtgacattgaattgcttcag
cttaaagagcaaggtttaacgcctgattcgattccggctgacgggcaaatcgtacaatta
cgtgccaactctaatatcagtaccggcggcgactcaatcgatatgaccgatcaaatgcac
gacagttataaacaattagcggtcggtattgccaaagcgatgggggcaaaagtctgcggt
gtggatttaatcattccggatttgaccaaagcagctgaaccgtctctgcgctcatggggt
gtgattgaagcaaactttaacccgatgatgatgatgcatattttcccttaccaaggaaaa
tctcgccgtttaaccaaagccgtgttaaaaatgctgttccctggactgccttaa
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