KEGG   Escherichia coli UM146: UM146_03135
Entry
UM146_03135       CDS       T02000                                 
Name
(GenBank) glutamate--cysteine ligase
  KO
K01919  glutamate--cysteine ligase [EC:6.3.2.2]
Organism
elu  Escherichia coli UM146
Pathway
elu00270  Cysteine and methionine metabolism
elu00480  Glutathione metabolism
elu01100  Metabolic pathways
elu01240  Biosynthesis of cofactors
Module
elu_M00118  Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:elu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    UM146_03135
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    UM146_03135
Enzymes [BR:elu01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.2  glutamate---cysteine ligase
     UM146_03135
SSDB
Motif
Pfam: Glu_cys_ligase
Other DBs
NCBI-ProteinID: ADN70043
LinkDB
Position
667186..668742
AA seq 518 aa
MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTD
FAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYG
TSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGY
FRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLG
YTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELY
APIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALA
DAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTL
DSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPL
EILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
NT seq 1557 nt   +upstreamnt  +downstreamnt
ttgatcccggacgtatcacaggcgctggcctggctggaaaaacatcctcaggcgttaaag
gggatacagcgtgggctggagcgcgaaactttgcgtgttaatgctgatggcacactggca
acaacaggtcatcctgaagcattaggttctgcactgacccataaatggattactaccgat
tttgcggaagcattgctggaatttattacaccagtggatggtgatattgaacatatgctg
acctttatgcgcgatctgcatcgctatacggcgcgcaatatgggcgatgagcggatgtgg
ccgttaagtatgccatgctatatcgcagaaggtcaggacatcgaactggcacagtacggc
acttctaacaccggtcgctttaaaacgctgtaccgtgaagggctgaaaaatcgctacggc
gcgctgatgcaaaccatttccggcgtgcactataatttctctttgccaatggcattctgg
caagcgaagtgcggtgatatctcgggcgctgatgccaaagagaaaatttctgcgggctat
ttccgcgttatccgcaattactatcgtttcggttgggtcattccttatttgtttggtgcg
tctccagcgatttgttcttctttcttgcaaggaaaaccaacgtcgctgccgtttgagaaa
accgagtgcggtatgtattacctgccgtatgcgacctctcttcgtttgagcgatcttggc
tataccaataaatcgcaaagcaatcttggtatcaccttcaatgatctctacgagtacgtg
gcgggccttaaacaggcaatcaaaacgccatcggaagagtacgcgaagattggtattgag
aaagacggtaagcggctgcaaatcaacagcaatgtgctgcagattgaaaacgaactgtac
gcgccgattcgtccaaaacgcgttacccgcagtggtgagtcgccttctgatgcgctgtta
cgtggcggcattgaatatattgaagtccgctcgctggatatcaacccgttctcgccgatt
ggtgtagatgaacaacaggtgcgattcctcgacctgtttatggtctggtgtgcgctggct
gacgcaccggaaatgagcagtagcgaacttgcctgtacacgcgttaactggaaccgggtg
atcctcgaaggtcgcaaaccgggcctgacgctgggtatcggctgcgaaaccgcgcagttc
ccgttaccgcaggtgggtaaagatctgttccgcgatctgaaacgcgtcgcgcaaacgctg
gatagcattaacggcggcgaagcgtatcagaaagtgtgtgatgaactggtcgcctgcttc
gataatcccgatctgactttctctgcccgtatcttaaggtctatgattgatactggtatt
ggcggaacaggcaaagcgtttgctgaagcgtaccgtaatctgctgcgtgaagagccgctg
gaaattctgcgcgaagaggattttgtcgccgagcgcgaggcgtctgaacgccgtcagcag
gaaatggaagccgctgataccgaaccgtttgcggtgtggctggaaaagcacgcctga

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