Streptococcus viridans: NCTC3166_01847
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Entry
NCTC3166_01847 CDS
T08046
Symbol
gshAB
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
svf
Streptococcus viridans
Pathway
svf00270
Cysteine and methionine metabolism
svf00480
Glutathione metabolism
svf01100
Metabolic pathways
svf01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
svf00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
NCTC3166_01847 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
NCTC3166_01847 (gshAB)
Enzymes [BR:
svf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
NCTC3166_01847 (gshAB)
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
GARS_A
ATP-grasp_3
Dala_Dala_lig_C
ATPgrasp_ST
ATP-grasp_4
R2K_3
Motif
Other DBs
NCBI-ProteinID:
VED68009
UniProt:
A0A447Z787
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All DBs
Position
1:1848051..1850306
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AA seq
751 aa
AA seq
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MTINQLLQKLDTSSPILQATFGLERENLRVTTDGHLAQTAHPSQLGSRNFHPTIQTDFSE
QQLELITPIAHSTKEARRLLGAISDVAGRSIDQSECLWPLSMPPQLTEEDIIIARLENEY
ERHYREGLAKKYGKKLQAISGIHYNMELGKDLVAALFQVSSYHLLKDFKNDLYLKLARNF
LRFRWLLTYLYGAAPLAEAGFYSQEYPQPIRSFRNSDYGYVNDENIQVSYTSLEQYVTDI
ENYVQSGELSAEKEFYSAVRFRGQKHNRAYLEQGITYLEFRCFDLNPFDHLGISQETLDT
VHLFLLGLLWLDDVENVDAVLKAAHDLNQKIACSHPLTALPDEADSSAILQAMEGLIQHF
ELPTYYQTLLDQMREALLHPQLTLSGQLLPHIQQDSLTAFGLEKAEEYHRYAWTAPYALK
GYENMELSTQMLLFDAIQKGLNVEILDEKDQFLKLWHGSHVEYVKNGNMTSKDNYVIPLA
MANKTVTKKILAAADFPVPAGAEFSSLEEGLAYYPLIKNREIVVKPKSTNFGLGISIFQE
PASLEAYHKALEIAFSEDVAVLVEEFIAGTEYRFFVLDGQCQAVLLRVAANVVGDGQHTV
RELIAIKNDNPLRGRDHRSPLEIIELGDIELLMLDQQGYGADDILPAGVKVDLRRNSNIS
TGGDSIDVTDSMHPSYKELAADMAKAMGAWACGVDLIIPDSSAISTKENPNCTCIELNFN
PSMYMHTYCAEGPGQSITPKILAKLFPEIDL
NT seq
2256 nt
NT seq
+upstream
nt +downstream
nt
atgacgattaatcaattactgcagaaactggatacatcaagccctattctccaagcgacc
tttggtctggagagggaaaatctgcgagtgacaactgatggacacttagctcaaactgct
catccgagtcagcttggttcccgcaatttccacccgaccatccaaacagacttcagcgaa
caacaactggaactaattacacctattgctcactctactaaggaagcgcggcgcttactg
ggagctatcagcgatgtggcaggccgctcaattgaccagagtgaatgcctgtggcctctg
tccatgccaccgcagctgactgaagaagatattatcatcgcccgtctggaaaacgaatac
gaacgccactaccgagagggtttagcgaaaaaatatggcaaaaaactacaggccatctct
ggtatccactacaacatggagctagggaaagatctggtcgctgctctctttcaagtcagc
tcctatcatttactcaaggactttaaaaatgacctctatctcaaactggctcgaaacttt
ctgcgtttccgatggctcttaacctatctctacggtgctgctcctctggcagaagccggc
ttctacagtcaggaatacccgcagcctatccgctcttttcgcaacagcgactatggctat
gtcaatgacgagaatattcaggtgtcctacacttctttggagcaatatgtaaccgatatt
gaaaactacgttcagtctggcgagctcagtgctgaaaaagaattttactcagccgttcgc
ttccgtggacagaagcacaatcgcgcctatctggagcagggtatcacctatctggaattc
cgctgcttcgatctcaatccttttgaccatttgggcattagccaagagaccttagatact
gtccatctctttttactgggcctgctctggctagatgatgtagaaaatgttgatgcagta
ttaaaagctgctcatgatttgaaccagaaaattgcttgtagccacccgctgactgccctg
ccagatgaggcagacagctcagccattctccaagccatggaagggctcatccagcatttt
gaactgccaacttactatcaaactttgctggaccagatgagagaggctctcttacatcct
cagctgacactgtcaggacagctcctgccccatatccagcaagattccttaacagctttt
ggtctagaaaaagcagaagaataccaccgctatgcctggactgctccttatgccctcaaa
ggctacgaaaatatggaactgtccacccagatgctactctttgatgctattcaaaagggg
ctaaatgtcgaaattttagatgaaaaggaccaatttctcaagctttggcatggtagtcat
gtagaatatgtcaagaacggcaatatgacctccaaggataactatgtcatccctttggcc
atggccaataaaacagtcaccaaaaagattttggcagcagctgactttcccgttccggct
ggagcagaattttcttctctagaagagggactggcctactaccctttgattaagaaccga
gaaattgttgtcaaacccaagtcaaccaacttcggactgggcatctctatcttccaagag
ccagctagcctggaagcttatcacaaggctctggagattgctttttcagaagatgtcgcc
gtcttagtggaggaatttatcgctggaacggagtaccgcttctttgtcttagacggacaa
tgccaagcagtcctcttgcgagtggcggccaatgtcgtcggagacggtcagcataccgtg
agagaattgattgccatcaaaaatgacaatcctctgcggggccgagatcatcgttcaccg
cttgaaatcattgaactgggggacattgaactgctcatgctggaccagcaaggctatgga
gcagatgatatcctgcctgctggagtcaaggttgacttgcggcgcaattccaacatttct
actggcggagactcgattgatgtcacagacagcatgcacccatcttataaggaactcgct
gcggacatggcaaaggctatgggagcctgggcctgtggcgttgatctcatcatccctgac
agctctgctatttccacaaaggaaaatcccaactgtacctgcatcgagctcaacttcaat
ccttctatgtatatgcacacctattgtgctgaggggccgggacaaagcattactccgaaa
atactagctaaacttttcccagaaatagacctataa
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