Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069: SGGBAA2069_c21330
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Entry
SGGBAA2069_c21330 CDS
T01444
Symbol
gshA
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
sgg
Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069
Pathway
sgg00270
Cysteine and methionine metabolism
sgg00480
Glutathione metabolism
sgg01100
Metabolic pathways
sgg01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sgg00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SGGBAA2069_c21330 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
SGGBAA2069_c21330 (gshA)
Enzymes [BR:
sgg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
SGGBAA2069_c21330 (gshA)
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
GARS_A
ATP-grasp_3
ATPgrasp_ST
Dala_Dala_lig_C
ATP-grasp_4
R2K_3
R2K_2
ATP-grasp
Motif
Other DBs
NCBI-ProteinID:
CBZ49305
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All DBs
Position
2182925..2185177
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AA seq
750 aa
AA seq
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MKLNGLLQKSPATLPILQATFGLERESLRISKTNHRVAQTKHPKCLGSRSFHPYIQTDYS
EPQVELITPIANSTSEALRFLGAITDIIGRSINKDEYLWPLSMPPKLSADEIAIASLEDD
WERQYRDHLAKVYGKILQSMSGIHYNMELGTDLVTALFEESDYTSLITFKNDLYLKLAQN
FLRFRWLLTYLYGASPIAEQGFLDKPLDKPVRSLRNSHLGYVNHDDIQVSYQSLERYISD
IEHYVNSGQLIAEKEFYSAVRLRGSKHNRDYLEKGITYLEFRCFDINPFDNRGITQETLD
TVHLFALALLWLDDSFAIDQDIADAKALNDRIALSHPLEKLPQEAPADLILSAMQAVVEH
FDLPEHYHTLLENVKAQIERPELTIGGRLVTEIDHLSLETFGQEKGQAYHDYAWHAHYAL
KGYENMELSTQLLLFDAIQKGVNVNILDENDQFLKLWHGDHVEYVKNANMTAKDNYITPL
VMENKVVTKKLLAQAGFPVPAGQEFADKDTALRYFSQVKDKAIVVKPKSTNYGLGISIFK
EPADLASYQSALDIAFAEDDTILVEEFISGTEYRFFVLDGKCEAVLLRIAANVVGDGTHT
IAELVDLKNQNPLRGYNHRSPLEIIELGDIERLMLEQQGYTPDDILPEGVKVDLRRNSNI
STGGDSIDVTETMNKSYQQLAAQMASAIGAWVCGVDLIIPDENLNASKEEPNCSCIELNF
NPAMYMHTYCHAGKGQALTPKILAKLFPEI
NT seq
2253 nt
NT seq
+upstream
nt +downstream
nt
atgaaattgaatggattactacaaaaatcacccgcgactctccctatccttcaagcaact
tttggcttagaaagagagagccttcgcattagtaaaacaaatcacagagttgcccaaact
aagcaccctaaatgtttgggaagtcgttcatttcacccttacattcagacggattacagc
gagccacaggtagagttaatcactccgattgccaactctaccagtgaagccctacgtttt
cttggggctatcacagatatcattgggcgctcaatcaacaaagatgagtacctttggcct
ttgtcaatgccaccgaaactatcggcagatgagattgctattgccagtctagaagatgac
tgggaacgccaataccgcgaccatttagcaaaagtgtatggcaagattctccaatccatg
tctggaatccattacaacatggagctgggtactgaccttgtgactgctctttttgaagaa
agtgactatacctctctaatcacctttaaaaacgacctctacctcaaattagctcaaaac
ttcctacgttttcgttggttattgacttatttgtatggggcttcgccaatagcagagcag
ggatttcttgacaaaccacttgataagcctgttcgctcactccgcaatagtcaccttggc
tatgttaatcatgacgacattcaagtatcctaccaaagccttgaacgttatatttctgac
attgaacattatgtcaattctggtcaactcattgctgaaaaagaattttactcagctgtc
cgacttcgtggcagcaaacacaatcgcgattatttagaaaaaggcattacgtaccttgag
tttcgttgttttgatatcaatccttttgacaatcgcggtatcacccaagagacacttgat
acggtgcaccttttcgccttggcacttctttggttagatgatagctttgctattgaccaa
gatattgctgacgcaaaagcgcttaatgaccgcatcgctcttagccacccacttgagaaa
ttgccacaagaagcacctgctgaccttatcctttctgccatgcaagcagtcgttgaacac
tttgatttgccagagcattatcacaccctactcgaaaatgttaaagcacagattgagcgc
cctgaattgaccattggtggacgtttagtgacagaaattgaccacctctctttggaaaca
tttgggcaagaaaaagggcaagcctatcacgactatgcttggcacgctcattatgccctc
aaaggctatgagaatatggaactttccactcaattattgctttttgatgccattcaaaaa
ggagtaaacgttaatattcttgatgaaaatgaccagtttctcaaactttggcatggtgac
catgttgaatacgtcaaaaatgccaatatgactgccaaagataattacattacaccactt
gtcatggaaaataaagtagtcacgaagaaattactagcacaagcaggcttcccagtccca
gctggacaagaattcgccgacaaagataccgcgctccgctatttttcacaagttaaagac
aaggctatcgttgtcaaaccaaaatcgactaactacggactaggtatctcaattttcaaa
gaacctgctgaccttgcttcttaccaaagcgctctagacattgcctttgctgaagatgac
acgattttagttgaagaatttatctctggaactgaatatcgcttcttcgttcttgatggt
aaatgcgaagcggtgcttctgcgaattgctgctaacgtggttggtgatggtacacacacg
attgcggaattggttgaccttaaaaatcaaaatccactccgtggctacaatcaccgttca
ccacttgaaatcattgaactaggcgacattgaacgcctcatgttagagcaacaaggatac
acaccagatgacattctccctgaaggtgtcaaggttgatttacgccgtaactctaacatt
tcaactggcggtgattcaattgacgttaccgaaaccatgaacaaatcttatcaacaacta
gcagctcaaatggctagcgctatcggtgcttgggtttgtggggtagatttgattattcct
gacgaaaatctcaatgctagtaaagaagagccaaactgctcgtgtatcgagctgaatttc
aatccagcaatgtacatgcacacttattgccacgcaggaaaagggcaagcattgacacca
aaaatcctagcaaaactcttcccagaaatctaa
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