Listeria monocytogenes EGD-e (serotype 1/2a): lmo2770
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Entry
lmo2770 CDS
T00066
Name
(RefSeq) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
lmo
Listeria monocytogenes EGD-e (serotype 1/2a)
Pathway
lmo00270
Cysteine and methionine metabolism
lmo00480
Glutathione metabolism
lmo01100
Metabolic pathways
lmo01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
lmo00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
lmo2770
09106 Metabolism of other amino acids
00480 Glutathione metabolism
lmo2770
Enzymes [BR:
lmo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
lmo2770
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
Dala_Dala_lig_C
GARS_A
ATP-grasp_3
ATPgrasp_ST
Motif
Other DBs
NCBI-GeneID:
986798
NCBI-ProteinID:
NP_466292
Pasteur:
LMO02770
UniProt:
Q8Y3R3
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Position
2850620..2852950
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AA seq
776 aa
AA seq
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MIKLDMTMLDSFKEDPNLRKLLFSGHFGLEKENIRVTSDGKLALTPHPAIFGPKEDNPYI
KTDFSESQIEMITPVTDSIDSVYEWLENLHNIVSLRSENELLWPSSNPPILPAEEDIPIA
EYKTPDSPDRKYREHLAKGYGKKIQLLSGIHYNFSFPEALIDGLYANISLPEESKQDFKN
RLYLKVAKYFMKNRWLLIYLTGASPVYLADFSKTKHEESLPDGSSALRDGISLRNSNAGY
KNKEALFVDYNSFDAYISSISNYIEAGKIESMREFYNPIRLKNAHTDQTVESLAEHGVEY
LEIRSIDLNPLEPNGISKDELDFIHLFLIKGLLSEDRELCANNQQLADENENNIALNGLA
QPSIKNCDNEDIPLADAGLLELDKMSDFIKSLRPEDTKLRAIIEKQKERLLHPEKTIAAQ
VKQQVTKEGYVDFHLNQAKTYMEETEALAYKLIGAEDMELSTQIIWKDAIARGIKVDVLD
RAENFLRFQKGDHIEYVKQASKTSKDNYVSVLMMENKVVTKLVLAEHDIRVPFGDSFSDQ
ALALEAFSLFEDKQIVVKPKSTNYGWGISIFKNKFTLEDYQEALNIAFSYDSSVIIEEFI
PGDEFRFLVINDKVEAVLKRVPANVTGDGIHTVRELVEEKNTDPLRGTDHLKPLEKIRTG
PEETLMLSMQNLSWDSIPKAEEIIYLRENSNVSTGGDSIDYTEEMDDYFKEIAIRATQVL
DAKICGVDIIVPRETIDRDKHAIIELNFNPAMHMHCFPYQGEQKKIGDKILDFLFD
NT seq
2331 nt
NT seq
+upstream
nt +downstream
nt
atgataaaacttgatatgaccatgcttgattcttttaaagaagaccctaatctccggaag
cttttattttctggacattttggtttagaaaaagaaaatattcgcgtaacttctgatgga
aaattggcccttacgccacatccagctatttttggtccaaaagaggataacccatatatt
aaaaccgatttttcggaaagtcagattgaaatgattaccccggtgacggactcgattgac
tctgtatatgaatggcttgaaaatcttcataatatcgtttcgctgcgctccgaaaacgaa
ctactttggccatctagcaatccgcccattttaccagcggaagaagatattccaattgct
gaatataaaacacccgatagtccggacagaaaataccgcgaacatttagcaaaaggctac
ggtaaaaaaatccaattattatctggcattcattataatttctcattcccggaagcttta
attgacggattatatgccaatattagcctcccagaagaatcgaagcaagattttaaaaat
cgtctatatttaaaagttgcaaaatactttatgaaaaatcgctggttgcttatttattta
actggcgcaagtccggtttaccttgctgatttctcgaaaacgaagcacgaagaatccctt
ccagacggtagtagcgcgcttcgtgatggaatttctcttcgaaatagtaatgctgggtat
aaaaacaaagaagctcttttcgttgattacaattcattcgacgcttatatttctagcatc
tctaactatatcgaagcaggcaaaatcgagagtatgcgcgaattttataacccaattcgt
ttgaaaaatgcgcataccgaccaaacagtcgaaagtttagcggagcacggcgtggaatat
ttagagattcgctctattgacctaaatccacttgaaccaaatggcatttctaaagacgag
cttgattttattcacctatttttaatcaaaggtttgctttcagaagatcgtgagttgtgc
gcaaataatcaacaattggccgatgaaaatgaaaataatattgccctaaatggcctcgcg
cagccctcaataaaaaattgcgataatgaagacataccactcgcagatgctgggctttta
gaactcgacaagatgagcgacttcatcaaaagtctgcgaccagaagacaccaaactccga
gcaatcatcgaaaaacaaaaagaacgtctgctacaccctgaaaaaacgattgctgcacaa
gtgaaacaacaagtaacaaaagaaggctacgtggacttccatttaaaccaagccaaaact
tatatggaagaaaccgaagctctagcctacaaattgattggcgcagaagatatggagctt
tccacccaaatcatatggaaagacgccattgcgcgtggcatcaaagtcgacgtattagac
cgagctgaaaacttccttcgcttccaaaaaggcgaccacattgaatatgtaaaacaagcg
agcaaaacgtccaaagataattacgtttccgttttaatgatggaaaacaaagtcgttaca
aagcttgtacttgcagaacacgatatccgagtgccctttggcgatagttttagtgaccaa
gctcttgcccttgaagcattctccctatttgaggataaacaaatcgtcgttaaaccaaaa
tccaccaactatggttggggaattagtattttcaaaaacaaattcacgctagaagattac
caagaagctttaaatatcgcattcagttatgatagctctgtcattattgaggagttcatt
cctggcgacgagttccgcttcttagttattaacgacaaagttgaagctgtactaaaacgt
gtccccgctaacgtaaccggcgacggaattcatacagtgcgcgagctggtcgaagaaaaa
aacacagatcctttgcgcggaacagatcatttgaaaccacttgaaaaaatccgtactggt
ccagaagaaactctaatgctttccatgcaaaacctttcttgggatagcattcctaaagca
gaagaaatcatctaccttcgcgaaaactccaacgtcagcacaggtggcgatagcattgac
tatactgaagagatggacgattacttcaaagagatagctattcgcgctacacaagtactt
gacgccaaaatttgcggcgtagacataattgttccacgtgaaacaattgatcgcgataaa
catgctatcattgagctaaacttcaacccagcgatgcacatgcactgcttcccttatcaa
ggagagcagaaaaaaattggtgataagattttagatttcttatttgactaa
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