Streptomyces genisteinicus: IAG43_01370
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Entry
IAG43_01370 CDS
T07903
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
sgj
Streptomyces genisteinicus
Pathway
sgj00270
Cysteine and methionine metabolism
sgj00480
Glutathione metabolism
sgj01100
Metabolic pathways
sgj01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sgj00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
IAG43_01370 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
IAG43_01370 (egtA)
Enzymes [BR:
sgj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
IAG43_01370 (egtA)
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GFIT
Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
QNP61707
UniProt:
A0A7H0HME1
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Position
297527..298801
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AA seq
424 aa
AA seq
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MRPPDTDGFGPGLSEDDAEDLLRCICFKTGPPRVVGVEVEWLVHDLERPAVPVDAERLRS
AHDEVRALSLTSALTFEPGGQLELSSAPAASLTECVDSTAADLRAVRTALRASGLALAGY
GLDPWQSPRRLLREPRYDAMERHLDRTGPAGRTMMCSSASVQVSLDAGEEEPGPLGHARR
WQLAHLLGAVLLAAFANSPARGGRPTGWKSARQAVWAAIDPVRALAPEPGAEPRSAWAAH
ALDAPVMCVRRAEGPWDSPAGLTFRQWLRSGTPRRPTREDLDYHLTTLFPPVRPRGHLEL
RMLDAQPGDDGWMVPTAVTAALFDDSEAAERVYRAVKPLAEYAGALPAPVSPLWVAAARV
GLADPAIHTAAVTAFDAALDALGRIGVRAELVAAVAAFHERYVLPGRSPADDLVLSPAAK
EPVT
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
atgcgtccgccagataccgacggcttcgggcccgggttgtccgaggacgacgccgaggac
ctgctccgatgtatctgcttcaagaccggtccgccccgtgtggtgggcgtcgaggtcgaa
tggctggtccacgacctcgaaaggcccgccgtcccggtggacgccgagcgtctgcgctcg
gcccacgacgaggtgcgcgccctctcgctcacctcggccctgaccttcgaaccgggcggc
cagctggaactcagctccgcgcccgccgcgtccctgacggagtgcgtcgactccaccgcc
gccgatctgcgcgccgtgcgcaccgcgctccgcgcctcgggtctggccctcgccggttac
ggtctcgatccctggcagtccccgcgccggctgctccgcgagccgcgctacgacgcgatg
gagcggcatctggaccgcaccggccccgccgggcgcaccatgatgtgctcgtcggcctcc
gtccaggtgtcgctggacgcgggcgaggaggaaccgggccccctcggccacgcgcggcgc
tggcagctcgcccatctgctgggcgcggtgctgctggccgcgttcgccaactccccggcg
cgcggcggccgtcccaccggctggaagtcggcccggcaggcggtgtgggcggccatcgac
cccgtgcgggcgctggcgcccgagccgggggccgagccgcgctccgcctgggcggcgcac
gcgctcgacgcgccggtgatgtgcgtgcgccgggccgagggcccgtgggacagcccggcg
gggctgacgttccgccagtggctgcggtcggggacgccccggcgtccgacgagggaggat
ctcgactaccacctgaccacgctgttccccccggtccggccccgcggtcacctggagctg
cgcatgctggacgcgcagccgggcgacgacggctggatggtgccgaccgccgtcaccgcg
gcgctgttcgacgattccgaggcggcggagcgggtgtaccgggcggtcaagccgctggcg
gagtacgccggtgccctgccggcgccggtcagtccgctgtgggtggcggccgcccgtgtc
gggctcgccgacccggcgatccacacggcggcggtcaccgccttcgacgccgcgctcgac
gccctggggcgcatcggcgtccgtgccgaactggtcgcggccgtcgccgcgttccacgag
cggtacgtgctgcccggccgttccccggccgacgacctcgtcctttcgcccgcggccaag
gagcctgtcacatga
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