Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52): KPN_03019
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Entry
KPN_03019 CDS
T00566
Symbol
gshA
Name
(GenBank) glutamate--cysteine ligase
KO
K01919
glutamate---cysteine ligase [EC:
6.3.2.2
]
Organism
kpn
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52)
Pathway
kpn00270
Cysteine and methionine metabolism
kpn00340
Histidine metabolism
kpn00480
Glutathione metabolism
kpn01100
Metabolic pathways
kpn01110
Biosynthesis of secondary metabolites
kpn01240
Biosynthesis of cofactors
Module
kpn_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
kpn00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
KPN_03019 (gshA)
00340 Histidine metabolism
KPN_03019 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
KPN_03019 (gshA)
Enzymes [BR:
kpn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
KPN_03019 (gshA)
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Paralog
GFIT
Motif
Pfam:
Glu_cys_ligase
Motif
Other DBs
NCBI-ProteinID:
ABR78425
UniProt:
A6TCV4
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All DBs
Position
complement(3318182..3319738)
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AA seq
518 aa
AA seq
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MIPDVSQALAWLEKHPQALQGIQRGLERETLRVNADGTLATTGHPPALGSALTHKWITTD
FAEALLEFITPVDGDIEHMLTFMRDVHRYTARQLGDERMWPLSMPCYIAPGQDIELAQYG
TSNVGRLKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGVEDAESGKEAISAGY
FRSIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPFEETGNGMYYLPYATSLRLSDLG
YTNKSQSNLGITFNDLHEYVAGLKRAIKTPSEEYAKIGLQKDGKYLQINSNILQIENELY
APIRPKRVTRRGETPSDALLRGGIEYIEVRSLDINPFSPIGVDAQQVRFLDLFMVWCALA
DAPEMSSDELLCTRTNWNRVILEGRKPGLTLGIGCESAQFPLAQVGKDLFRDLRRVAQTL
DSIHGGQAYQQVCDELLACFDDPELTFSARILRSMIEEGIGGTGRALADRYRTQLREEPL
EILSEDDFIAERDASVARQKKVEAEDSEPFEALLARHA
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
ttgatcccggacgtatcacaggcgctggcctggctggaaaaacatccgcaggctctgcag
ggtattcaacgtggtctggagcgggaaacgctgcgcgtgaacgcagacggcacccttgca
acgaccggtcaccctccggcgttaggctcagcgctgacgcataaatggattaccaccgat
tttgccgaagctttacttgagttcattacgccagtagatggcgatattgagcatatgctg
acctttatgcgcgatgtccatcgctataccgcgcgtcagcttggcgacgagcggatgtgg
ccgctgagcatgccatgctatatcgcccccggtcaggatattgagctggcgcagtacggc
acctctaacgtggggcgcctgaaaacgctatatcgcgaggggctgaagaaccgctatggc
gcgctgatgcagactatctccggcgtgcactataacttctccctaccgatggccttctgg
caggcaaaatgtggtgtggaagatgccgagagtggtaaagaggccatttcggcgggctat
ttccgctcaattcgtaactactatcgctttggctgggtgatcccctatctgtttggcgcc
tcgccggcgatttgctcctcattcctgcaaggcaaaccgacaacgctgccctttgaggaa
acgggcaacggcatgtattacctgccgtatgccacctcgctgcgcctcagcgaccttggt
tataccaataagtcgcaaagcaatctcggaattacgtttaacgatctgcacgagtatgtg
gcaggattgaagcgggcgattaaaacgccgtcggaagagtacgccaaaatcgggctgcag
aaagacggcaagtacctgcagatcaacagcaacattctgcagattgaaaatgaactttat
gcgccgatccgcccgaaacgcgtcacccgtcggggcgaaaccccgtccgatgcgctgttg
cgcggtggtattgagtatatcgaagtgcgttcgctggatatcaatccgttctcgccgatc
ggcgttgacgcccagcaggtgcgtttcctcgacctgtttatggtctggtgcgcgctggcc
gacgcgccggagatgagcagcgatgagctgctgtgcacccgcaccaactggaatcgggtg
attctggaagggcgtaagccgggcttaacgctggggattggctgcgaaagcgcgcagttc
ccgctggctcaggtgggcaaagatctgttccgcgatttacgccgcgtggcgcagaccctg
gacagtatccacggtggccaggcatatcagcaggtctgcgacgagctgctggcctgcttt
gacgatccggaattaaccttctcagcccgcattctgcgttctatgattgaagaaggcatt
ggcggtaccggccgtgcgcttgccgatcgttaccggacgcagctgcgcgaagagccgctg
gagatcctgagcgaagacgattttatcgccgagcgcgacgcgtcggtggcgcgacagaag
aaagtggaagctgaagacagcgagccgtttgaggcgctgctggcgcggcacgcgtag
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