Streptomyces phaeolivaceus: F9278_42720
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Entry
F9278_42720 CDS
T07107
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate---cysteine ligase [EC:
6.3.2.2
]
Organism
sphv
Streptomyces phaeolivaceus
Pathway
sphv00270
Cysteine and methionine metabolism
sphv00340
Histidine metabolism
sphv00480
Glutathione metabolism
sphv01100
Metabolic pathways
sphv01110
Biosynthesis of secondary metabolites
sphv01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sphv00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
F9278_42720 (egtA)
00340 Histidine metabolism
F9278_42720 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
F9278_42720 (egtA)
Enzymes [BR:
sphv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
F9278_42720 (egtA)
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Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
QFR01799
UniProt:
A0A5P8KGB2
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All DBs
Position
complement(9381912..9383186)
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AA seq
424 aa
AA seq
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MSDSLSGCTEQRSAVTEAEVEALVRGICFKTGPPRTLGVELEWQVHELRDPRLPATPARL
EAAYAALRTLTLNSPLTVEPGGQLELSSAPAGSLMECVGSVSADLDAVRATLREADLGIS
GFGHEPWNPPTRYLHEPRYDAMEIYLDRFGPEGRSMMCSSASVQVCLDAGYEEPGPLGHQ
RRWWLAHQLGAVLVAAFAHSPLARGRVTGWRSTRQALWAAMDPGRTNAPALDGDPRAAWA
RLVLDAPVMCVRADEGPWGVPGAMTFREWTRSDTPPSRADLDYHLTTLFPPVRPRGHLEL
RMIDAQPGEDGWIVPLAVTAALFEDPEAAETAYRTVKPLAERAGARPAPRNPLWDTAIRD
GLADPELREAATVCFAAAAEALPRIGASAEVRDAVAAYTDRHVARGRCPADDLLDLFHGK
DIPA
NT seq
1275 nt
NT seq
+upstream
nt +downstream
nt
atgtcagattcgctgagtggctgtacggagcaacgctccgcggtcaccgaggcagaggtg
gaggccctggtacggggcatctgcttcaagaccggtccaccccgcaccctcggtgtcgaa
ctggaatggcaggtccacgagctgcgtgatccgcggctcccggcaacacccgcacgactg
gaagcggcctacgccgcactgcggaccctgaccctgaactccccgctgaccgtcgagccc
ggcgggcagttggagctcagctcggcaccggccggctccctgatggagtgcgtcgggtcc
gtctcggccgacctggacgccgtacgcgccacactgcgcgaggcggacctcggcatcagc
ggcttcggccacgaaccctggaaccccccgacccgctacctccacgagccccggtacgac
gcgatggagatctatctcgaccgcttcggccccgagggccggtccatgatgtgctcctcc
gcctccgtgcaggtctgtctcgacgccgggtacgaggagccgggccccctcggccatcag
cggcgctggtggctggcgcaccagctcggcgcggtgctggtggcggcgttcgcgcactcc
ccgctggcgcgcggccgggtcaccggctggcgttcgacccggcaggccctgtgggcggcc
atggacccgggccggaccaacgccccggcgctggacggcgacccgcgcgcggcgtgggcc
cggctcgtgctggacgcgccggtgatgtgcgtccgggcggacgagggcccctggggtgtg
cccggagcgatgacgttccgggagtggacgagatccgacaccccgccgagccgcgccgac
ctcgactaccacctgacgaccctgttcccgccggtgcgcccgcgcggtcatctggagctg
cgcatgatcgacgcccagcccggtgaggacggatggatcgtgccgctcgccgtgacggcg
gcgctgttcgaggacccggaggcggccgagaccgcctatcggaccgtgaagccgctcgcc
gagcgggcgggcgcacggccggcgccgcgcaatccgctgtgggacacggccatccgcgac
ggactggccgatcccgaactgcgggaggcggcgaccgtctgcttcgccgcggcggccgag
gcgctgccccggatcggcgcgagcgccgaggtacgggacgcggtcgcggcgtacaccgac
cgccatgtggcccggggccgctgccccgccgacgatctgctggacctgttccacgggaag
gacatccccgcatga
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