Lysinibacillus fusiformis: HR49_12005
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Entry
HR49_12005 CDS
T03655
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
lfu
Lysinibacillus fusiformis
Pathway
lfu00270
Cysteine and methionine metabolism
lfu00480
Glutathione metabolism
lfu01100
Metabolic pathways
lfu01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
lfu00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
HR49_12005
09106 Metabolism of other amino acids
00480 Glutathione metabolism
HR49_12005
Enzymes [BR:
lfu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
HR49_12005
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATPgrasp_ST
GARS_A
ATP-grasp_3
Dala_Dala_lig_C
ATP-grasp_4
Ins134_P3_kin
Motif
Other DBs
NCBI-ProteinID:
AJK90045
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Position
complement(2406028..2408286)
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AA seq
752 aa
AA seq
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MDYKKMLVNDHVKPYLLKAHYGIEKESKRVDLSGNLAKTDHPKSISQQDDHPYIQRDFSE
LQMELITPVTDTLNELFDYLAAIHDVAYRSMGENEMLWPLSMPPQLPEKDEDIVMAKLKS
AENVRYRQSLSNSYGRRKQMLCGVHFNFEFGDELIQALFNAQSEIKEYQHFKTEIYLKAT
RNYLHYRWLVTYFYGASPRSEKNFFEENLLNEVVRSIRSSKYGYTNSKDVQVSYSSIQNY
VSDLSSMVKRGLLSTEREFYSPVRLRGGHHVSELEDNGIKYIELRNIDLNPFETYGISYE
QAEFLHLFLIYLLWKDEGENSDEWVKIGECYNDIVALEHPLEHTQFEKEAKKMIDEMKHL
ATILNLTISDTLFVHLKEMLMDPSKTLAGRLFEESEKCSQRQLATSIAKENYKKSWDKPY
QLAGFTDMELSTQILMFDAIQQGIQVEILDRQDQFLKLKLKEHVEYVKNGNITSKDNYVS
TLIMENKTVTKKILQQHGFRVPKGKEFQTIEQALRSYDLFSSKPFVVKPKTTNYGLGISI
FKEGSNYEDYQKAIILAFKEDSSILVEEFLKGTEYRFFVLNDRVKAVLLRVPANVKGDGK
HTIEELVMQKNRNPLRGRDHRTPLEIIQLGELENLMLKAQGYQVNSIPKMDEIIFLRENS
NISTGGDSINVTDLIPDDYKKIAVDAVASLGAKICGIDLIIENGNKNAYGIIEANFNPSM
YMHIYPYKGETRRLTMHIIHYLFPELLLSQSN
NT seq
2259 nt
NT seq
+upstream
nt +downstream
nt
atggattataaaaaaatgttagttaatgaccatgtgaaaccatacttattaaaagctcat
tatgggattgaaaaagaaagtaaacgagtagatttatccggaaatttagctaaaacggat
catcctaaaagtatttctcaacaagatgaccatccgtatattcagcgggatttttcagaa
ttacagatggaattaattacacctgttactgatacattgaacgaactttttgattattta
gcagcaatccatgatgttgcttatcgttctatgggtgagaatgaaatgctttggccatta
agcatgccgccacagttaccagagaaagacgaagatattgtaatggcgaaattgaaaagt
gctgaaaatgttcgatatcgacaatcattatcgaattcttatggccgtcgtaaacaaatg
ctttgcggtgttcattttaacttcgagtttggcgatgagttaattcaagcattatttaac
gcacaatcggagattaaagagtatcagcattttaaaacagagatttatctaaaagctaca
agaaactatttgcactatcgatggttagttacttatttttatggagcttctcctagaagt
gaaaagaatttctttgaagaaaatttattgaatgaggtagtaagaagcattagaagcagt
aaatatggttatacgaattcgaaagatgttcaagtgtcatatagtagtatacagaattat
gtatcagacctttcttcgatggttaaaagagggcttctatcaacagaaagagaattttat
tcacctgtccgtttaagaggaggacatcatgtttcagaactagaggataacggtattaaa
tatattgaattgcgaaatatagatttaaatccttttgaaacatacggcattagctatgaa
caagcagaatttctccatcttttcttaatttatttactatggaaagatgaaggggaaaat
agtgatgagtgggtaaaaataggcgaatgttacaatgatatagtggctcttgagcatcca
ttagagcatacacaatttgaaaaagaagcaaaaaaaatgattgatgagatgaaacattta
gcaacaattttaaatttgactatttcagatacgttatttgttcatctgaaagaaatgcta
atggatccaagtaagactttagctggaagactttttgaagaaagtgaaaaatgcagtcaa
cgtcaattggctacgtcgattgctaaagaaaattataaaaaatcatgggataagccatat
caattagcaggatttactgacatggagttgtctactcagattttaatgtttgatgcgatc
caacaaggaatccaagtagaaatcttggatcgacaagaccaatttctgaagctgaaatta
aaagaacatgttgaatatgtaaaaaatggtaatataacaagtaaagataattatgtatcc
actttaattatggaaaataaaacagtaacaaagaaaattcttcaacaacatggatttcgt
gtgccgaaagggaaggaatttcagacaattgaacaggctctacgtagctatgatctcttt
tcctccaaaccttttgttgtgaagccgaaaacaacaaactatggattaggaatatcaatc
ttcaaagaaggctcaaattatgaagattatcaaaaagccattatattagcatttaaagaa
gactcttccatattagtagaagaatttctaaaaggaacagaatatcgattttttgtatta
aatgatcgagtaaaagctgttttactaagagttcctgcgaatgttaaaggtgacggtaaa
catacaatcgaagagttagtcatgcaaaagaatcgtaacccgttaagaggaagagaccat
cggacacctttagaaattatccagttaggtgaattagagaatcttatgcttaaagctcaa
ggatatcaagtcaattcgattcctaaaatggatgaaatcatctttctgcgtgaaaattcc
aatattagtacaggtggagactcgattaatgtgacggatctaattcctgatgattataaa
aaaatagcagtggatgcagtagcttcattgggagctaaaatttgtggtattgatttgatt
attgaaaatggtaataaaaatgcttatggaattattgaagccaactttaatccatctatg
tatatgcacatctatccatataaaggagagactcgacgtttaactatgcatatcatacat
tatttatttcctgaactattgcttagtcagtcaaattag
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