Streptomyces laculatispora: P8A22_02835
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Entry
P8A22_02835 CDS
T09657
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
slai
Streptomyces laculatispora
Pathway
slai00270
Cysteine and methionine metabolism
slai00480
Glutathione metabolism
slai01100
Metabolic pathways
slai01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
slai00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
P8A22_02835 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
P8A22_02835 (egtA)
Enzymes [BR:
slai01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
P8A22_02835 (egtA)
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Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
WLQ39051
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All DBs
Position
731495..732811
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AA seq
438 aa
AA seq
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MSPDTPGGHGPPGHPPPLGEVEAEDLLRGICFKTGPPRIVGVELEWLLHDRDHPRSPVQH
DRLEAAATAVRALSLNAAVTFEPGGQLELSSRPADSLMACVNDTADDLVAVRAALGRLGL
TPVGIGVDPWQSPRRLLREPRYDAMETALDRWGPAGRAMMCTTASVQVCLDAGEEEPGPL
GYGRRWQLAQLLGAVLVAAFANSPFQQGRPTPWQSTRQSLWTDLDPLRTLAPAGQLPPRD
AWASYVLDTPVMCIRGDAGPWSVPEGLSLRDWIRSGVPRRPVRADLDYHITTLFPPVRPR
GHLELRMIDAQSGDDGWLVPLAVTTALFDDPEAAETVYRTVKPLAETAGPLAAPRNPLWL
AAARDGLADPELRVAAAACFELALEALPRMGATQAVQDAVAGFHDRYVARGRCPADDLRA
LLAPDRTDGRYDPEGTLS
NT seq
1317 nt
NT seq
+upstream
nt +downstream
nt
atgtcacccgacacacccggcggccacggtccgcccggtcacccccctcccctcggcgag
gtcgaggcggaggacctactgcgcggcatctgcttcaagacgggaccgccgcgcatcgtg
ggggtcgagctcgaatggctcctgcacgatcgcgaccacccgcgcagtcccgtccagcac
gaccgtctcgaagcggccgcaacggccgtccgggcgctgtccctgaacgccgcggtcacc
ttcgaacccggcggccagctggagctcagctcgcgccccgccgattccctcatggcgtgc
gtcaatgacaccgccgacgacctcgtcgccgtacgtgccgcgctcggccggctgggtctc
actccggtcggaatcggcgtcgatccctggcagtcgccgcgcagactgctgcgcgaaccc
cgctacgacgccatggagaccgccctcgaccggtggggaccggccggccgcgccatgatg
tgcacgaccgcgtccgtccaggtctgtctggacgcaggtgaggaggagcccggtccgctc
ggctacgggcggcgctggcagctggcccagctgctgggtgcggtgctggtggcggcgttc
gcgaactcgcccttccagcagggcaggccgacgccgtggcaatcgacgcgtcagtccctg
tggaccgacctcgacccgctgcgtacgctcgcccccgccggtcagctgccgccccgcgac
gcctgggcctcgtacgtcctggacacgccggtcatgtgtatccgcggcgacgccgggccg
tggtcagtgccggagggcctcagcctgcgggactggatccggtccggggtgccgcggcgc
ccggtccgggccgatctcgactaccacatcaccacactgttcccgccggtccgtccgcgc
ggacacctggagctgcgcatgatcgacgcgcagtccggtgacgacgggtggctcgtgccg
ctcgcggtcaccactgccctgttcgacgacccggaggccgcggagaccgtgtaccgcacc
gtcaaaccactggccgagaccgcggggccactggccgctccgcgcaatccgctctggctc
gctgccgcccgtgacggactggccgaccccgaactgcgggtagcggccgccgcctgcttc
gagctggccctggaggcgctgccccggatgggcgcgacccaggcggtgcaggacgcggtg
gcgggcttccacgaccgatacgtcgcacggggccgatgccctgccgacgatctccgggcg
ctgctcgcaccggaccggacggatggccggtacgacccggaggggaccctctcatga
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