Streptococcus lactarius: J4854_06880
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Entry
J4854_06880 CDS
T07623
Symbol
gshAB
Name
(GenBank) bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
slat
Streptococcus lactarius
Pathway
slat00270
Cysteine and methionine metabolism
slat00480
Glutathione metabolism
slat01100
Metabolic pathways
slat01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
slat00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
J4854_06880 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
J4854_06880 (gshAB)
Enzymes [BR:
slat01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
J4854_06880 (gshAB)
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATP-grasp_3
GARS_A
RimK
Dala_Dala_lig_C
ATPgrasp_ST
ATP-grasp_4
R2K_3
Motif
Other DBs
NCBI-ProteinID:
QUB38269
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Position
1357037..1359301
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AA seq
754 aa
AA seq
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MTINQLLQKLEPTSPILQANFGIERESLRVDRQGKLAHTPHPSCLGARSFHPYIQTDFCE
FQMELITPVAKSTTEARRFLGAITDVAGRSISKDELLWPLSMPPRINAQEIQVAQLENEF
ERHYRNYLAEKYGTKLQAISGIHYNMELGKDLVEALFQESHQIDIIAFKNALYLKLAQNY
LRYRWVITYLFGAAPVAEQGFFDQEVPELVRSFRNSDHGYVNKEKIQVSFASLEDYVSDI
ENYIEQGDLIAEKEFYSAVRFRGQKVNRSFLDKGITYLEFRNFDLNPFERIGISQTTMDT
VHLLLLAFLWLDAPENVDQALAQGHALNEKIALSHPLEPLPSEAETQNITTALDQLVQHF
GLGDYHQGLVKQVKDTFADSSQTLAAQLLPHIKDKSLSDFALDKALAYHDYDWTAHYALK
GYEDMELSTQMLLFDAIQKGLHFEILDEQDQFLKLWHKDHVEYVKNGNMTSKDNYVVPLA
MANKTVTKKILADAGFPVPAGDEFTSLEQGLAYYPLIKGKQIVVKPKSTNFGLGISIFQE
PASLDNYKKALEIAFAEDTAVLVEEFIPGTEYRFFILDGRCEAVLLRVAANVVGDGKHTI
RELVAQKNVNPLRGRDHRSPLEIIKLGDIEQLMLTQQGYAPDDILPEGKKVNLRRNSNIS
TGGDSIDVTETMDSSYQELAAAIATSMGAWACGVDLIIPDKTQPASKEKPHCTCIELNFN
PAMYIHTYCAEGPGQAITPKILDKLFPEVATSQT
NT seq
2265 nt
NT seq
+upstream
nt +downstream
nt
atgactataaatcaactgcttcaaaagctggagcctactagccctatccttcaagctaac
tttggaattgaacgcgaaagtcttcgtgtcgatagacagggaaaattagcacatacgcct
cacccttcctgcctaggagctcgaagtttccacccttatattcaaacagatttttgtgag
tttcagatggaactcatcacaccagttgctaaatctaccactgaggctcgtcgatttctt
ggagccattaccgatgtagctggacgttccatcagtaaagatgaacttctctggcccttg
tccatgcctcctcgtatcaacgcccaagaaatccaagttgcccaactggaaaatgaattt
gaacgccattatcgtaactacctggccgaaaaatacggaactaaactacaagctatctca
ggtatccactataatatggaactagggaaagatttggttgaagccctattccaagaaagt
caccagattgatataattgctttcaaaaacgccctctatcttaagctggctcagaactat
ttgcgctatcgttgggtgattacctatctctttggtgctgcacctgttgctgagcaaggc
ttcttcgatcaagaagtgccagaactcgtgcgttccttccgaaacagcgaccatggttat
gtcaataaggaaaaaatacaagtatcttttgcaagcctagaggactatgtttctgacatc
gaaaactatatcgaacaaggtgatttgattgcggaaaaggaattttactcggctgttcgt
ttccgtggacaaaaggttaatcgctccttccttgacaagggaatcacctacctagaattc
cgtaacttcgacctcaacccctttgagcgtatcggtattagccaaactaccatggatacc
gtacacctactccttctagccttcctctggctggatgcccctgaaaatgttgatcaggct
ctggctcaaggtcacgcgctgaatgaaaaaattgccctctctcatcctttagaacctcta
ccttctgaagctgaaactcagaacattacgacagctctagaccaactggtgcaacatttt
gggcttggtgactatcatcaaggtctggtcaaacaagttaaagatacctttgcagattcc
agtcagacactagctgctcaacttcttcctcatatcaaagacaagtccctttctgacttt
gcccttgacaaggcgcttgcctatcatgattacgactggactgcccactatgctcttaag
ggttatgaggatatggaactttctacccagatgctgctctttgatgccattcaaaagggg
cttcattttgaaatcctagatgagcaggatcaattccttaaactctggcataaagatcat
gttgagtacgtcaaaaatggtaacatgacctcaaaagacaactatgtagttcctcttgcc
atggctaataaaaccgtgaccaaaaaaattctggctgatgctggcttccctgtccctgcc
ggcgacgaatttaccagtctagaacaaggtctagcctactatcctcttatcaagggcaag
caaattgtggttaaaccaaaatcaaccaacttcggtctgggcatttccattttccaagag
cctgccagccttgataactataagaaagctctcgagattgcctttgcagaagatacagct
gttcttgttgaagaatttatcccaggaaccgaataccgtttcttcattctggacgggcgt
tgtgaggctgtcctccttcgtgtcgctgctaatgttgtcggtgatggcaaacacaccatt
cgtgaattagtcgctcagaaaaatgtcaatccattgcgaggccgtgaccaccgctcacct
ctggaaatcattaagctaggagacatcgaacaattgatgttgactcagcaaggttatgca
cctgatgatattctcccagaagggaaaaaggtcaatctccgccgtaactccaacatctct
acaggtggcgactctattgatgtcactgagaccatggattcatcctatcaagaattagct
gcagctatagcgactagcatgggggcctgggcttgcggggttgacctcatcattccagat
aaaactcagcctgctagcaaggaaaaacctcattgcacttgtatagagctcaacttcaat
cccgctatgtatattcacacctattgtgctgaaggtcctggacaagctatcactccaaaa
atcctagacaagctttttccagaagttgccacaagtcaaacctaa
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