Enterococcus silesiacus: ATZ33_12625
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Entry
ATZ33_12625 CDS
T04218
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
ess
Enterococcus silesiacus
Pathway
ess00270
Cysteine and methionine metabolism
ess00480
Glutathione metabolism
ess01100
Metabolic pathways
ess01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
ess00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
ATZ33_12625
09106 Metabolism of other amino acids
00480 Glutathione metabolism
ATZ33_12625
Enzymes [BR:
ess01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
ATZ33_12625
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATP-grasp_3
RimK
GARS_A
ATPgrasp_ST
Dala_Dala_lig_C
R2K_2
R2K_3
Motif
Other DBs
NCBI-ProteinID:
ALS02196
UniProt:
A0A0S3KDA7
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Position
complement(2731242..2733512)
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AA seq
756 aa
AA seq
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MKFKELLQEKIVRPYVMAARFGLEKESQRTTFDGQLAMTDHPEVLGNRSYHPYIQTDFSE
TQMELITPVASSINEMLRYLAAIHDVALRSMNKHEMLWPLSMPPKLPLKDEDIKIAKLDQ
FEGILYRRYLAREYGKRKQMVSGIHFNFEYAIELVEQLFSEQTEYETIEEFKNILYMKVS
RNYLRYRWLITYLFGASPVSESGYFTAQEEHPKEPVRSIRNSSFGYKNNENVKVSYESLQ
HYINDIHRMVENGILSEEKEFYSAVRLRGGKQMADLPKTGVRYIELRNLDLNPFAPLGVD
EESLEFIHLFMLYLLWTDEKEAPNDWVATGDFLNEQVALGHPFAQVKLLAEGDRIFAEMD
EMIEALGLFRAKKSLEVHRAQLRTPDLTIAGKMWTIIENNSNQELGIIFGKEYQGMAFEK
PYQLAGFRNMELSTQLFLFDIIQKGVEVEILDEQEQFLKLKHHEHIEYVKNANMTSKDSY
IVPLIMENKTVTKKVLAQAGFCVPAGDEFDTLENAEQAYVKYSEKAFVIKPKTTNYGLGI
TIFKEGASLADYTEALQLAFKEDSAVLIEEFLPGTEYRFFVLDDQVRAIMLRVPANVVGD
GVRSVEALVAEKNLDPLRGTHHRSPLELIQLGDVERLMLKEQNLLTTSVPEKDQIVYLRE
NSNVSTGGDSIDVTDNFDESYKQIAVEAVQALGAKICGIDLIVPDKSVKGTKNSRTYGII
EANFNPAMHMHAYPHSGKGRHLTMDVLKMLYPEVFE
NT seq
2271 nt
NT seq
+upstream
nt +downstream
nt
atgaaatttaaagagttgttacaggaaaaaatcgtgcgtccatatgttatggcggcacga
tttggattagaaaaagaaagtcaacggactacattcgatggtcaactagcaatgactgat
catccagaggttttggggaatcgttcgtatcatccatatattcaaactgattttagcgaa
actcaaatggaattgatcacaccagtagctagctccatcaatgaaatgctacgttatctt
gcagccatccacgatgtggcgctgcgttcaatgaataaacatgagatgctttggccgctt
agtatgccgccgaaattaccactaaaagatgaagatatcaaaattgccaagctcgaccag
tttgaaggaattttgtatcgtcgctatttagcacgagaatatgggaaacgcaagcaaatg
gttagcggtattcacttcaattttgaatatgcgatcgagttagttgagcaacttttctca
gaacaaacagaatatgaaacaatcgaagagtttaaaaacattttatatatgaaggtttcc
cgcaattacttacgttaccgctggctgattacctatctgtttggagcgtctcctgtcagc
gaatcaggttattttactgcacaagaagagcacccaaaagaaccagtcagaagtattcgt
aatagttcatttggctataaaaataatgaaaatgtcaaagtatcatatgaatcgttacaa
cactatattaatgatattcatcgaatggttgagaacggtatattatcagaagaaaaagaa
ttttattcagcggttcgattacgcggtggtaaacaaatggctgatttgcctaaaaccggt
gttcgttacatcgaacttagaaatctagatctaaacccatttgcgccattaggtgtggat
gaagagtcacttgaatttatccatttatttatgttgtatttactgtggacggatgaaaaa
gaagcgccaaatgattgggttgcaactggggatttcttaaatgagcaagttgctttaggg
catccttttgctcaagtgaagcttttagcggaaggtgaccgtatttttgctgaaatggat
gaaatgattgaagcgttaggtctatttagagcaaaaaaatcattggaagttcaccgagca
cagttaagaactccagatttaacgatcgccggaaaaatgtggacgattattgaaaataat
tctaatcaggaattggggattatttttggaaaagaatatcaaggaatggcttttgaaaaa
ccttatcaattagctggatttagaaatatggagttatccacgcaattatttttatttgat
attatccaaaaaggtgtagaagtcgaaatattggatgaacaagaacaatttttaaaactt
aaacatcatgagcatattgagtatgttaaaaatgcgaatatgaccagtaaagatagctac
attgttccactgatcatggaaaataaaacggtcactaaaaaagtcttggcccaagcaggc
ttttgtgtgccggcaggcgacgagtttgacacattggagaatgccgaacaagcatatgta
aaatattcagaaaaagcttttgtaatcaaacccaaaacgacgaactatggtttgggaatc
acgatctttaaagaaggagcttcattagctgattatacagaagcactgcaattagcgttt
aaagaagattcagcggtgttgatcgaagaattcttgccaggcacagaataccgcttcttt
gtcctagacgatcaagtgcgtgcaatcatgctgcgtgtgcctgctaatgttgtaggggat
ggtgtgcgctctgtggaggcgttggtagcagaaaaaaatcttgatccattaaggggaacg
catcatcgctcgccattggaactgattcagctaggtgatgtggagcgtttgatgttaaaa
gagcaaaatctattgacgacttctgttccggaaaaagatcaaatcgtttatctgcgtgaa
aattcaaatgtcagcacgggtggtgattccatcgatgtgacggataattttgatgaaagc
tataagcaaatcgctgttgaagctgttcaggcattaggagcgaagatttgtgggatcgac
ttgattgtacctgacaaatcagtcaaaggaaccaaaaacagccgaacatacggtattata
gaagcaaactttaatccagcaatgcatatgcacgcgtatccacattcaggtaaagggcgt
catttgacaatggatgtattgaaaatgttatacccagaagtatttgaataa
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