Mannheimia granulomatis: A4G16_07540
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Entry
A4G16_07540 CDS
T06759
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
mgra
Mannheimia granulomatis
Pathway
mgra00270
Cysteine and methionine metabolism
mgra00480
Glutathione metabolism
mgra01100
Metabolic pathways
mgra01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mgra00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
A4G16_07540
09106 Metabolism of other amino acids
00480 Glutathione metabolism
A4G16_07540
Enzymes [BR:
mgra01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
A4G16_07540
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATP-grasp_3
Dala_Dala_lig_C
ATPgrasp_ST
GARS_A
Motif
Other DBs
NCBI-ProteinID:
QIM67227
UniProt:
A0A6G8JJA3
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Position
1593133..1595409
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AA seq
758 aa
AA seq
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MKLQQIIRENHLALLFQQGCFGLEKESQRIDIKGNIVTTPHPAIFGNRSYHPYIQTDFAE
SQLELITPPNAKLEDTFRWLSAIHEVVLRSLPEDEYIFPLSMPAGLPPEDLIQEAQLDNP
ADVKYREHLSANYGKYKQMVSGIHYNFQLSVEFVEKAFALQTEYQDLKTFQNALYMKLTN
NFLRYQWILLYLLSATPTVESQYFYGKSPLAEGQLVRSLRSSPYGYVNSPDVVVNHDSLE
SYVESLEAQVEKGLLIAEKEFYSNVRLRGGKKARDLLENGVKYAEFRLFDLNPFSPYGIT
LEDAKFIHYFLLGMLWLDETSGQKEVEIGKQKLYQVALEDPRTETAFRAEGETILTQILV
MLNELNTKEELKDLVREKLSQFADPRKTLNGRLITAIEQFGSYKALGAKLAQDYKAQAFE
RFYALSAFDNMELSTQALFFDLIQQGINVELLDENDQFLALQFGNHLEYVKNGNMTSHDQ
YISPLIMENKVVTKKVLAKAGFNVPKSVEFTTIEQAIAHYPLFEGKAVVIKPKSTNYGLG
ITIFQQAVKNREDFAKAIEIAFREDKEVMVEDYLIGTEYRFFVLGDETLAVLLRVPANVI
GDGIHSVKELVEMKNTDPLRGDGSRTPLKKIALGEIEQLQLKEQGLTIDSIPAKDQVVQL
RANSNISTGGDSIDMTDQMHESYKQLAVGIAHAMGAKVCGVDLIIQDLTQPAQPNLDSWG
VIEANFNPMMMMHIFPYQGKSRRLTKAIINMLFPEIRS
NT seq
2277 nt
NT seq
+upstream
nt +downstream
nt
atgaaattacaacaaattatccgggaaaatcatttagcactactgtttcaacagggttgt
tttggtttggaaaaagagagccaacgtattgatattaaaggcaatatcgtcactacccca
catccagctatttttggtaatcgctcatatcatccttatatccaaactgattttgctgaa
agtcaattagagttaatcacaccacccaatgcgaaattggaagatacttttcgctggctt
tctgccattcacgaagtggttttacgatctttgcctgaagatgaatacatcttcccattg
agcatgcctgccggcttaccaccggaagatctgattcaagaagcacagctcgataatcca
gcggatgttaaatatcgagagcatctatctgccaattacggtaagtataaacaaatggtc
agcggcatacattataatttccaactttctgttgaatttgtagaaaaagcctttgctttg
caaaccgaatatcaagatttaaaaaccttccaaaacgcactttatatgaagcttactaat
aacttcttgcgttatcagtggatcttgctttacttactttctgctacaccgacagtggaa
tcgcaatatttttacggaaaatcaccgcttgcggaggggcaattagttcgtagtttgcgt
tctagcccttatggttatgtcaattcgccagatgtagtagtcaatcacgatagcttggaa
agctacgttgaaagccttgaagctcaagttgaaaaaggtttattaattgcagagaaagaa
ttctattcaaacgtgcgtttacgtggtggcaaaaaagcacgtgatttactagaaaatggt
gtgaaatacgctgaattccgtttatttgacttaaacccattttcaccttacggcataaca
ctagaggatgcaaaatttatccactatttcttacttggaatgctttggctggacgaaaca
agcggtcaaaaagaggtagaaatcggcaaacagaaactttaccaagtcgcattggaagat
cctcgtacggaaactgctttccgagctgaaggagaaacgatcttaacgcaaatcttagta
atgctgaacgaattaaataccaaagaggaactgaaggatctcgtgcgtgaaaaattatcc
caatttgccgatcctcgcaaaacacttaatggacgtttaattacggctattgagcaattt
ggcagctataaagctttaggtgcaaaattagcccaagattataaagcacaagcctttgag
cgtttttatgctttatctgcatttgacaatatggaactttccacccaagcgctatttttt
gatttaattcaacaaggtattaatgtcgaattattagacgaaaacgaccaattccttgcc
cttcaatttggcaatcatttggaatatgtgaaaaacggcaatatgaccagtcacgatcaa
tatatttcgccgttgattatggaaaacaaagtcgtcactaaaaaagtattggcaaaagcc
ggatttaatgtgccgaaaagtgtggaatttaccacaattgaacaagctattgctcactat
ccgctttttgaaggcaaagcagtggtaattaagccaaaatccactaactatggtttgggc
atcactattttccaacaagcggttaaaaatcgagaagattttgcaaaagctattgaaatt
gccttccgtgaagataaagaagtgatggtagaagattatttaatcggtaccgagtatcgc
ttttttgtcttaggtgatgaaaccttagcagtcctgctacgagtgcctgcaaacgtcatt
ggtgacggtattcacagcgtgaaggaattagtagaaatgaaaaatactgatcctctacgc
ggcgatggttctcgcaccccgcttaagaaaattgccttaggtgaaattgagcaactacag
ctcaaagaacaaggcttaaccatcgattctataccggcaaaagatcaggtagtacagcta
agggctaactcaaatatcagtaccggtggagattctattgacatgactgaccaaatgcac
gagagctataaacaacttgctgtcggcattgctcatgcaatgggagctaaagtgtgtgga
gtggatttaatcattcaagatctcacccagcctgcacagcctaaccttgactcttggggt
gtgatcgaagcaaacttcaatccaatgatgatgatgcatattttcccctatcaaggaaaa
tctcgccgcttaactaaagcaattattaatatgctgtttccggaaattagatcttag
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