Streptomyces dengpaensis: C4B68_03745
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Entry
C4B68_03745 CDS
T06611
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
sdx
Streptomyces dengpaensis
Pathway
sdx00270
Cysteine and methionine metabolism
sdx00480
Glutathione metabolism
sdx01100
Metabolic pathways
sdx01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sdx00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
C4B68_03745 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
C4B68_03745 (egtA)
Enzymes [BR:
sdx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
C4B68_03745 (egtA)
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Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
AVH55058
UniProt:
A0A2L2MEP2
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Position
777223..778557
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AA seq
444 aa
AA seq
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MSDSVSDCAERRSAVTEAEVEALVHGICFKTGPPRYLGVEVEWLIHELRTPRLPVPPARL
EAAYAALRTLPLRSALTVEPGGQLELSSAPASSLMECIGSVSADLDAVRATLREAGLGLS
GYGHDPWNPPNRFLHEPRYDAMERYLDRAGPEGRAMMCSSASVQVCLDAGYEEPGPLGHG
RRWWLAHQLGAVLVAAFAHSPLARGRHTGWRSTRQSLWTAMDPGRAGAPPLDGEPRAAWA
RHVLDASVMCVRAPSGPWTVPEGMSFRQWTRSASPPDRADLDYHLTTLFPPVRPRGHLEL
RMIDAQPGDDGWIVPLAVTAALFDDAEAAEIAYRTVKPLAERADSLAAPRNPLWRDAARY
GLADPELHEAAVACFAAAAEALPRLGATTEVLDAVAEFNDRYVARGRCPADDLLGPFDGR
SPTQPHGPSHGPSYGRFHGKDIRT
NT seq
1335 nt
NT seq
+upstream
nt +downstream
nt
atgtccgattcggtgagtgactgtgcggagcgccgctccgccgtcaccgaggccgaggtg
gaggcgctcgttcacggcatctgcttcaagaccggtccgccccggtacctcggtgtcgaa
gtggaatggctcatccatgagctgcggacgccgcggctccccgtaccacccgcacgactt
gaagcggcgtacgccgcactgcggaccctgcccctgcgttcggcgctcaccgtcgaaccc
ggcggtcagctggagctcagctccgctcccgcgtcttctctgatggagtgcatcgggtcc
gtctccgccgacctcgacgccgtccgcgcgacactgcgcgaggcaggtctcggcctcagc
ggctatggccacgatccctggaaccccccgaaccgcttcctccatgagccccgttacgac
gccatggagcgctacctcgaccgcgcggggccggaaggccgcgccatgatgtgcagctcc
gcctccgtccaggtgtgcctggacgccgggtacgaggagccgggcccgctcgggcacggg
cgccgctggtggctggcgcaccagctgggcgcggtcctggtggccgcgttcgcccactct
ccgctcgcccgcgggcggcacaccggctggcgctccacgcggcagtcgctgtggacggcg
atggaccccgggcgggccggcgcccctcccctggacggcgagccacgggccgcctgggcc
cggcacgtcctggacgcgtcggtgatgtgcgtacgggcgccgagcggcccctggaccgta
ccggaaggcatgagtttccggcagtggacccggtcggcgtcgccgccggaccgggcggat
ctcgactatcacctgacgaccctgttcccaccggtgcgtccgcgcggtcatctcgaactg
cgcatgatcgacgcacagccgggcgacgacggctggatcgtgccgctcgccgtgacagcg
gccctcttcgacgacgcggaggccgccgagatcgcgtaccggaccgtcaaaccgctcgcc
gagcgggcggactcgctggccgcgccgcgcaatccgctgtggcgggacgccgcgcggtac
ggcctggcggacccggagctgcacgaggccgccgtcgcctgtttcgcggcggcggccgag
gccctgccccggctcggcgccaccaccgaggtcctggacgccgtggcggagttcaacgac
cgctatgtggcccggggccgctgccccgccgacgatctgctcggccccttcgacgggcga
tcccccactcaaccgcacgggccgtctcacggcccgtcctacggtcggttccacgggaag
gacatccgcacatga
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