Enterococcus lactis: I4Q40_00580
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Entry
I4Q40_00580 CDS
T07069
Symbol
gshAB
Name
(GenBank) bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
elac
Enterococcus lactis
Pathway
elac00270
Cysteine and methionine metabolism
elac00480
Glutathione metabolism
elac01100
Metabolic pathways
elac01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
elac00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
I4Q40_00580 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
I4Q40_00580 (gshAB)
Enzymes [BR:
elac01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
I4Q40_00580 (gshAB)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATP-grasp_3
GARS_A
ATPgrasp_ST
RimK
Topo-V_HhH_2_2nd
R2K_3
R2K_2
Dala_Dala_lig_C
Motif
Other DBs
NCBI-ProteinID:
QPL60185
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Position
112204..114471
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AA seq
755 aa
AA seq
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MMNFKQLLLHDNARPFIDQARFGIEREGQRVDLAGNLAKTDHPAIFGDRSYHPYIQTDFS
ETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLSLPPALPEKDEEIIIAKLK
NFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLFSHQEEFQDFSEFKTELYLKT
ARNFLRYRWMITYLFGASPMSEKNYFINESHPQEPVRSIRNSALGYTNHPNVKVSYASMK
QYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADLAKTGVRYIELRNIDLNPYARLGIN
PEQVRFLQLFLMYMLWTEEKEDSDQWVAEGTTRNNKVALEQPSHQTEFHQEGKEILEGMK
QMLVELDWLDSLYLVEEALTQMDHPEQTLAAKLYQEAQLSSQQEVAVALGHQYYKESHER
PYQLAGFREMELSTQIFMFDAIQKGVQVKVLDESDQFLRLQYQDHVEYVKNANMTSKDSY
IVPLIMENKTVTKKVLKETGFRVPGGAEFSSMEEAVKAYPRFADQAFVIKPKSTNYGLGI
TIFKEGADLEDYQAGLAIAFREDSSVLVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGD
GIRTVKELVEEKNSDPLRGTNHRAPLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRE
NSNISTGGDSIDMTDEFSEAYKKIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGII
EANFNPAMHMHVYPFAGKGRRLTMNVLKLLYPEIF
NT seq
2268 nt
NT seq
+upstream
nt +downstream
nt
atgatgaattttaagcaattattattgcatgacaatgcgcgcccttttatcgaccaagct
cgatttggtatagaacgggaaggacagcgggttgatcttgcaggaaatctagcaaaaacc
gatcatccagcaatctttggcgatcgatcttatcacccctatatccaaacagattttagc
gaaacacaaacagagatgatcacccctgttaccgattctattcccgaattatttcagtat
ctggctgctgtttatgatgtgactgctcgttctataccgaaagaagagatgatctggcca
ttaagtttgccacctgccttaccggaaaaagacgaagaaatcattattgcaaaattaaaa
aatttcgaagatgttttgtatcgacgttatttagcaaaagaatacgggaagcgaaaacaa
atggtaagcggcatccatttcaattttgaatttggtgacgaattgttaagaacattgttc
agccatcaggaagaatttcaggatttttctgaattcaaaacagaactttatttgaaaaca
gcgagaaattttttacgctatcgctggatgatcacttatttatttggtgcttcaccgatg
agtgagaaaaactattttataaatgaatcgcatccgcaagaacctgttcgcagtattcga
aacagtgcgctaggctacacgaatcatccaaatgtgaaagtttcctatgcttccatgaaa
cagtatttagcagatattgagcgaatgatcgaagaagggaaactttcggaggagaaagaa
ttttatacaccgcttcgtttccgaggcggaaagaaagtcgcagatctggcaaaaacaggc
gttcgttatattgaattgcggaatatcgatctgaacccttacgcaaggctgggaatcaat
ccggaacaagttcgtttcttacaattattcctgatgtatatgctatggacagaagaaaaa
gaagacagtgaccaatgggtggcagaaggtacgactcgaaataacaaagtagcactagaa
caaccatcacatcagactgaatttcatcaagaaggtaaagaaatccttgaagggatgaag
caaatgctggttgaattggattggttggattctctttatttagtggaggaagcattgact
caaatggatcatcccgaacaaacgttagcagcgaaactctatcaagaagcacagctatcg
agccagcaagaagttgctgtggcattggggcatcaatattataaagaaagtcatgaacgt
ccctatcagttggccggttttcgcgaaatggaactttctactcagatatttatgttcgat
gccatccaaaaaggtgtccaagtcaaagtattagatgagtcggatcaatttttgcgtctg
caataccaagaccatgtagaatatgtgaaaaatgcaaacatgacaagtaaggacagctat
atcgttccacttatcatggaaaacaaaacagtaacgaaaaaagttttaaaagaaactggg
ttccgagtaccaggaggcgcagaattttcatccatggaagaagccgtaaaagcttatcca
agatttgccgatcaggcctttgtgatcaaacctaagtccacaaattacgggttaggtatc
acgattttcaaggaaggggctgatctggaggattatcaagcaggattggcgattgctttt
cgtgaagacagctcggttttagtagaagaatttatgccgggaacggaatatcgtttcttt
gtaattgatggagaagtccaagccatcatgttgcgagtccctgctaatgttattggtgac
ggtatccgaacagtgaaagaacttgttgaagaaaaaaatagtgaccctttgcgtggaacg
aatcatcgtgcaccgttggaattgatccaattaggcgaattagaacaattgatgttgaaa
gaacaagggttaacgatcgaatcagttcctcaagccaatcaaattgtttatctaagggag
aactcaaatatcagtacgggcggtgattcgatcgatatgacggatgaattttctgaagct
tacaaaaaaatcgccgtttctgcggtagaagcactaggagctaaaatcagtggtattgat
ttgatcataccagataaagaaatcgatcctacaaccgataaaaaagcatacgggatcatc
gaagcaaatttcaatccagcgatgcatatgcatgtttatccttttgcaggaaaaggcaga
agattgacgatgaatgtattgaaattgttatatcctgaaatattttaa
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