Acinonyx jubatus (cheetah): 106979040 Help Entry 106979040         CDS       T04657                                  Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism aju  Acinonyx jubatus (cheetah) Pathway aju04010   MAPK signaling pathway aju04014   Ras signaling pathway aju04015   Rap1 signaling pathway aju04022   cGMP-PKG signaling pathway aju04066   HIF-1 signaling pathway aju04068   FoxO signaling pathway aju04072   Phospholipase D signaling pathway aju04150   mTOR signaling pathway aju04151   PI3K-Akt signaling pathway aju04152   AMPK signaling pathway aju04211   Longevity regulating pathway aju04213   Longevity regulating pathway - multiple species aju04520   Adherens junction aju04910   Insulin signaling pathway aju04913   Ovarian steroidogenesis aju04923   Regulation of lipolysis in adipocytes aju04930   Type II diabetes mellitus aju04931   Insulin resistance aju04932   Non-alcoholic fatty liver disease aju04960   Aldosterone-regulated sodium reabsorption aju05010   Alzheimer disease aju05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:aju00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     106979040    04014 Ras signaling pathway     106979040    04015 Rap1 signaling pathway     106979040    04066 HIF-1 signaling pathway     106979040    04068 FoxO signaling pathway     106979040    04072 Phospholipase D signaling pathway     106979040    04022 cGMP-PKG signaling pathway     106979040    04151 PI3K-Akt signaling pathway     106979040    04152 AMPK signaling pathway     106979040    04150 mTOR signaling pathway     106979040  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     106979040  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     106979040    04923 Regulation of lipolysis in adipocytes     106979040    04913 Ovarian steroidogenesis     106979040   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     106979040   09149 Aging    04211 Longevity regulating pathway     106979040    04213 Longevity regulating pathway - multiple species     106979040  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     106979040   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     106979040   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     106979040    04932 Non-alcoholic fatty liver disease     106979040    04931 Insulin resistance     106979040  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:aju01001]     106979040   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:aju04090]     106979040 Enzymes [BR:aju01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      106979040 Protein kinases [BR:aju01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    106979040 CD molecules [BR:aju04090]  Proteins   106979040 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like B2 DUF4476 Motif Other DBs NCBI-GeneID:  106979040 NCBI-ProteinID:  XP_026905914 UniProt:  A0A6J1YN10 LinkDB All DBs Position A2:complement(159246198..159385908) Genome browser AA seq 1381 aa AA seqDB search MGAGAGRGAATAPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLVMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTSCPATVINGQFVERCWTHGHCQKVCPTICKSHGCTADGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCRDLHNKCKNSRRQG CHQYVIHNNRCIPECPSGYTMNSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGC TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQAEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRKSFSSPGAEDSRPSRKRRALADAGNVTAAVPTVPGF PNTSSSVPTSPEEHKPFEKVVNKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYVS ARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVS RRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGP LIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPRE KITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGF TCHHVVRLLGVVSKGQPTLVVMELMVHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAA EIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVR WMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNC PERVTDLMHMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEMEF EDMESVPLDRASHSQREEAGGRDGVSSLGLKRNYEDHIPYTHMNGGKKNGRILTLPRSNP S NT seq 4146 nt NT seq  +upstreamnt  +downstreamnt atgggcgccggggctgggcggggggcggccaccgcgccgctgctggtggcggtggccgcg ctgctgctgggcgccgcgggccacctgtaccccggagaggtctgccctggcatggatatc cggaacaacctgacgaggctgcacgaactggccaactgctcggtcattgaaggtcatttg cagatactgctcatgttcaaaacgaggcccgaggacttccgagacctcagtttccccaaa ctcgtcatgatcactgattacctgctgctcttccgggtgtacgggctggagagcctgaag gacctcttccccaacctcacggtcatccggggctcgcgcctcttcttcaactacgcgctg gtcatcttcgagatggtgcacctgaaggagcttggtctctacagcttgatgaacattacc cggggctccgtccgcatcgagaagaataatgagctgtgctacctggccaccatcgactgg tcgcgcatcctggattcggtggaggataattacattgtattgaacaaagacgacaacgag gagtgtggggacatttgtccaggcactgcaaagggcaagaccagctgccctgccactgtc atcaacgggcagtttgtggagcgttgttggacacacggccattgccagaaagtttgtccg accatctgcaagtcgcacggctgcacggccgacggcctctgctgccacagcgagtgtttg ggcaactgctccgagcccgacgaccccaccaagtgcgtggcctgtcgcaacttctacctg gacggcaggtgcgtggagacctgcccgcccccctactaccacttccaagactggcgctgc gtgaacttcagcttctgccgggacctgcacaataaatgcaagaactcccggagacagggt tgccaccagtatgtcattcacaacaacaggtgcatccctgagtgcccctcggggtacacg atgaattccagcaacctgatgtgtactccctgcctgggcccctgtcccaaggtctgccac atcctggaaggcgagaagaccatcgactcggtgacatctgcccaggagctccgaggctgc accgtcgtcaacggaagcctaatcatcaacattcgagggggcaacaacctggcagctgag ctggaggccaacctcggactcattgaagaaatttccgggtatctgaagatccggagatcc tatgctctcgtgtcactctcctttttccggaagttacggctgattcggggagagaccttg gaaatcgggaactactctttctatgccttggacaaccagaacctgaggcagctatgggac tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataatcccaaa ctctgcttgtcggaaattcacaagatggaggaggtttcaggaaccaaggggcgccaggag cggaacgacattgccctgaagaccaatggggaccaggcgtcttgtgaaaatgaactactt aaattttcttacattcggacatcttacgacaagatcttgctgaaatgggagccgtactgg ccccctgacttccgagacctccttggcttcatgctcttctacaaagaggccccttatcag aatgtgaccgagttcgacgggcaggacgcgtgtggctccaacagctggacggtggtggac attgacccgcctctgaggtccaatgaccccaagtcgcagaaccacccagggtggctgatg cggggtctcaagccctggacccagtatgccatctttgtcaagaccttggtcaccttttct gatgagcgccgcacgtatggggccaagagtgacatcatctatgtccagaccgatgccacc aacccttccgtccccctggatcctatctcggtttcgaattcctcctctcagatcattctg aagtggaagcctccctcggaccccaacggcaacatcacgcactacctggtgttctgggag aggcaggcggaggacagcgagctatatgagttggattattgcctcaaagggttgaagctg ccttcccggacctggtccccgccgttcgagtccgagggctcccagaagcacaatcagagt gagtacgaggagtccgctggcgagtgctgctcgtgtcccaaaaccgactctcagatcctg aaggagctggaggagtcctctttcaggaagacgttcgaggattacctgcacaatgtggtt ttcgtgcccagaaaatccttttcaagccctggtgctgaggacagtaggccatcgcggaag cgcagggccctcgccgacgctgggaacgtgacggccgccgtgcccacggtgcctggtttc cccaacacttccagcagcgtgcccacgagcccggaagagcacaagcccttcgagaaggtg gtgaacaaagagtcgctggtcatctctggcctgcgtcacttcactggctaccgcatcgag ctgcaggcttgcaaccaagatgcccccgaggagaggtgcagcgtggctgcctacgtcagc gccaggaccatgcccgaagccaaggcagacgacattgttggccctgtgacccatgaaatc ttcgagaacaacgtggttcacttgatgtggcaagagcctaaagaacccaatggattgatc gtgctgtatgaagtgagttaccgacggtatggtgatgaggagctgcacctctgtgtctcc cgtagacactttgctctggagcggggctgcaggctgcgagggctgccaccggggaattac agtgtgcgagttcgggccacctccctggcgggcaacggctcctggacagaagccacttat ttctatgtgacagactatttagatgtcccatcgaacattgcaaaaattatcatcgggcct ctcatctttgtctttctcttcagtgttgtgattggaagtatttatctattcctgagaaag aggcagccggatggcccactggggccgctgtatgcttcttcaaaccctgagtacctcagt gccagtgatgtgtttccctgctctgtgtatgtgccggacgagtgggaggtgcctcgggag aagatcactctcctgcgcgagctggggcagggctccttcggcatggtgtacgagggcaat gccagggacatcgtcaagggcgaggcggagacccgcgtggcggtgaagacggtcaacgag tccgccagtctgcgagagaggatcgagtttctcaacgaggcctcagtcatgaagggcttc acctgtcatcacgtggtccgcctcctgggggtggtgtccaaaggccagccgacgctggtc gtgatggagctgatggttcacggagacctgaagagctacctccgctccctgcggccggag gctgagaataaccctggccgccctccccctactctgcaagagatgattcagatggcggcg gagatcgccgacgggatggcgtacctgaatgccaagaagtttgtgcaccgggatctcgca gcccgaaattgcatggtggcccacgacttcaccgtcaaaattggagacttcggaatgacc agagacatctatgaaacggattactaccggaaaggaggcaagggtctgctccccgtgcgg tggatggcaccggaatccctgaaggacggggtcttcaccacttcttctgacatgtggtcc tttggtgtggtcctttgggaaatcaccagcttggcggaacaaccttaccaaggcctgtct aatgaacaggtgttgaaatttgtcatggacggaggatatttggaccaacctgacaactgt ccggagagagtcaccgacctgatgcacatgtgctggcagttcaatcccaagatgcggccc accttcctggagatcgttgacctgctcaaggacgacctgcaccccagctttccggaagtt tccttcttccacagcgaggagaacaaggcgcctgagagtgaggagttggaaatggagttt gaggacatggagagtgtccccctggatcgggcctcacactcacagagggaagaggccggg ggccgggatggagtgtcctcgctgggcctcaagcggaactacgaggaccacatcccctac acccacatgaacgggggcaagaaaaacggacggattctgaccctgccgaggtcgaatcct tcctaa

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