Castor canadensis (American beaver): 109682903
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Entry
109682903 CDS
T04791
Symbol
Alox12
Name
(RefSeq) arachidonate 12-lipoxygenase, 12S-type
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan00590
Arachidonic acid metabolism
ccan01100
Metabolic pathways
ccan01523
Antifolate resistance
ccan04726
Serotonergic synapse
ccan04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
109682903 (Alox12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
109682903 (Alox12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
109682903 (Alox12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
109682903 (Alox12)
Enzymes [BR:
ccan01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
109682903 (Alox12)
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Paralog
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
109682903
NCBI-ProteinID:
XP_020014063
UniProt:
A0A8B7U2Q7
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All DBs
Position
Unknown
AA seq
663 aa
AA seq
DB search
MGRYRISVATGAWLFSGSHNRVRLWLVGAHGEAELELQLRLARGEVEEFDLDVPQDLGPL
QFVKLRKQHSLVDDAWFCDCITVRGPGACAQAAFPCYRWVQGQGVLSLPEGTARLAGDNA
LDVFQKHREKELKERQQMYCWATWKQGLPQTIAADCKEDLPPNMRFHEEKRLDFEWTLKA
GALEMVLKRVCTLLSSWNCLEDFDQIFWGQKTALAEKVHQCWQDDELFGYQLLNGANPML
LRRSTALPSRLVLPSGTEELQTQLEKELQNGSLFEADFILLDGISANVIQGEKQYLAAPL
VMLKMDPNGKLLPMVIQIQPPNPSYPTPTLFLPSDPPLAWLLAKIWVRSSDFQLQELQYH
LLNTHLVAEVIAVATMRCLPGLHPIFKLLVPHIRYTMEINTRSRTQLISDGGIFDQAVST
GGGGHIQLLRRAVAQMTYCSLCPLDDLADRGLLGIPSALYAQDALRLWKIIARYVEGIVH
LFYQRDDVVRGDPELQTWCREITEVGLCQAQDRGFPICFQSQAQLCHFLTMCIFTCTAQH
AAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDIQKSCLQMTITWHLGRR
QPDMVPLGHHKEKYFSSPKATAVLSQFRTDLENLENEITARNEQLELPYEYLKPSCIENS
ITI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggacgctaccgcatcagcgtggcgacgggggcctggctcttctctgggtcgcacaac
cgcgtgcggctgtggctggttggggcgcacggggaggcggagctggagctgcagctgcgg
ctagcgcggggcgaggtggaggagtttgaccttgacgttccccaggacttgggacctcta
cagttcgtgaagttgcgcaaacagcactcactggtggacgacgcgtggttctgcgactgc
atcacggtgcggggccccggagcctgcgcccaggcggccttcccctgctaccgctgggtg
caaggccagggcgtcctgagcctgcccgagggcaccgcccgtctagcaggagacaatgcc
ttggatgtcttccagaaacatcgagagaaggaactgaaagaaagacaacagatgtactgc
tgggccacctggaagcaaggtttaccccaaacaatagctgcagactgtaaggaggatcta
cctccaaatatgagatttcatgaggagaagagactggactttgaatggacactgaaggca
ggggctctggagatggtcctcaaacgtgtttgcaccctcctgagctcctggaactgccta
gaagactttgatcagatcttctggggccagaagactgccctggctgagaaggttcaccag
tgctggcaggatgatgagctttttggctaccagttactcaatggtgccaaccccatgctg
ttgagacgctccaccgctctgccctccaggctggtgctgccctcagggacagaggagctg
cagacccaattggagaaggaactccagaatggttccctgtttgaggctgactttatcctg
ctagatggaatttcagccaatgtgatccaaggagaaaagcagtacctggctgcccccctt
gtcatgctgaagatggaccccaatgggaagctgctacccatggtcatccagattcaacct
cccaatcccagctacccaaccccaacactgttcctgccctcagatcctccacttgcctgg
ctcctggccaagatctgggtccgaagttcagattttcaactgcaggagctccagtatcat
ttgctgaacactcatctagtggctgaggtcatcgctgtcgccaccatgaggtgcctccca
ggactgcaccctattttcaagctcctggtcccccatatccgctacactatggaaatcaac
acccggagccgaactcaactcatctcagatggaggaatctttgatcaggcagtgagcaca
ggtggagggggccacatacagctgctccgtcgggcagtggctcagatgacatactgctcc
ctctgtcctctggatgatctggctgaccggggtcttctgggaatcccaagtgctctgtat
gcccaggatgctttgcggctctggaagatcattgcccggtatgtggaggggatcgtacat
ctcttctaccagagggatgacgtcgtgagaggggaccctgagctgcagacctggtgtcgg
gagatcactgaggtggggctgtgccaggctcaggaccgaggttttcctatctgtttccag
tcccaggctcaactctgccatttccttaccatgtgtatcttcacatgcactgcccagcat
gcagccatcaaccagggccagctcgactggtatgcctgggtccctaatgccccatgcaca
atgaggatgcctccacccaccaccaaggaggatgtgacaatggccacagtgatggggtca
ctacctgatatccagaagtcctgtcttcaaatgaccatcacatggcatctgggtcgccgc
cagccagacatggtgcctctggggcatcacaaagaaaaatatttctcaagccccaaggcc
acagctgtgctaagccaattccgaacagatctggaaaacttggaaaatgagattacagct
cggaatgaacaacttgaactaccctatgaatacctgaagcccagctgcatagagaacagt
atcactatctga
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