Castor canadensis (American beaver): 109692146 Help Entry 109692146         CDS       T04791                                  Symbol Hdac6 Name (RefSeq) histone deacetylase 6 isoform X1   KO K11407   histone deacetylase 6 [EC:3.5.1.98] Organism ccan  Castor canadensis (American beaver) Pathway ccan04613   Neutrophil extracellular trap formation ccan05014   Amyotrophic lateral sclerosis ccan05034   Alcoholism ccan05203   Viral carcinogenesis Brite KEGG Orthology (KO) [BR:ccan00001]  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     109692146 (Hdac6)  09160 Human Diseases   09161 Cancer: overview    05203 Viral carcinogenesis     109692146 (Hdac6)   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     109692146 (Hdac6)   09165 Substance dependence    05034 Alcoholism     109692146 (Hdac6)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:ccan01009]     109692146 (Hdac6)   09182 Protein families: genetic information processing    03019 Messenger RNA biogenesis [BR:ccan03019]     109692146 (Hdac6)    04131 Membrane trafficking [BR:ccan04131]     109692146 (Hdac6)    03036 Chromosome and associated proteins [BR:ccan03036]     109692146 (Hdac6) Enzymes [BR:ccan01000]  3. Hydrolases   3.5  Acting on carbon-nitrogen bonds, other than peptide bonds    3.5.1  In linear amides     3.5.1.98  histone deacetylase      109692146 (Hdac6) Protein phosphatases and associated proteins [BR:ccan01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      109692146 (Hdac6) Messenger RNA biogenesis [BR:ccan03019]  Eukaryotic type   mRNA surveillance and transport factors    mRNA cycle factors     Stress granule specific factors      109692146 (Hdac6) Membrane trafficking [BR:ccan04131]  Autophagy   Aggrephagy    Other aggrephagy associated proteins     109692146 (Hdac6) Chromosome and associated proteins [BR:ccan03036]  Eukaryotic type   Histone modification proteins    HDACs (histone deacetylases)     Class II HDACs      109692146 (Hdac6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hist_deacetyl zf-UBP Motif Other DBs NCBI-GeneID:  109692146 NCBI-ProteinID:  XP_020028174 UniProt:  A0A8C0WS58 LinkDB All DBs Position Unknown AA seq 1273 aa AA seqDB search MEKRASGARGPTGRREFGGANQGRSLRKGLRSSRGRAAASPAMTSTGQDSTTTRHRKSRH NPQSPSHDLSITSKRSVKKGAAPRSTPNLAEIKKKGKMKKLSQKVEEDLIVGLQGLDLNP EVKIVTGTGLVFDEQLNEFYCLWDDSFPESPERLHAIKEQLIQESLLDRCVCFQARFAEK EELMLVHSLEYIDLMEMTQYMNEGELRVLASTYDSVYLHPNSYSCACLASGSVLRLVDAV LGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQKKHRIQRVLIVDWDVHHGQ GTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSATGFGQGQGYTINVPWNQVGMRDAD YIAAFLHILLPVAFEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKL ILSLEGGYNLHSLAKGVSASLHTLLGDPCPMLESPGVPCRSAQTSLSCTLEALEPFWGIL VRSVDTPEEDGEEEDTVEETEEGPWEASALPVLTWPVLQHRTGLVYDQRMMSHCNLWDNH HPETPQRILRIMCHLEELGLAAHCLILPVRAATDAELLTCHSAEYVERIRATEKMKTREL HREGANFDSIYLCPSTFTCAQLAAGAACRLVEAVLSGEVLNGIAVVRPPGHHAEHAAACG FCFFNSVAVAARHAQTISGRALRILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTF FPMGDEGASSQIGRAEGTGFTVNVPWNGPRVGDADYLAAWHRLVLPIAYEFNPELVLVSA GFDAARGDPLGGCQVSPEGYAHLTHLLMGLANGHIILILEGGYNLTSISESMAACTHSLL GDPPPLLPLLRPPQPGALASITETIQVHRRYWRSLRVMKVEDKETSSASKPVTKKASHPT NPKLAKGVTMPEGKILRAGMKKATSTLPAKESTPGQTKSKTANVATLTQDQCLERATGGA KLDQTTSEETVERATVDQTTSEESVGGATVGQATTEESVGEATVDQATTEESVEEAAVEQ ATTEETVEGATGDEATSVESVRGARVDQVNSEAATGEVMLDQTTSEETAGESEVIQTPLA SNTDKQTPAASPVRGATAQSSPCQLIGSHRILELGNETQETLESQTLGEEGLLGEAAGGQ DTDCSVLMQDFGELGDSDEDIFYAVTPLSWCPHLGAVCPIPEEGLDTAQPCERCGTFEEN WLCLSCYKIYCSRYVSAHMVCHFEASRHPLVLSCVDLSAWCYICQAYVHHQDILHVKNVV HQIKFGEDIPQPH NT seq 3822 nt NT seq  +upstreamnt  +downstreamnt atggaaaagagggcatccggtgcccgaggccccacaggtcgccgggaatttggcggtgcg aaccaagggcggagtttgagaaaagggctgcgctcaagccgcggcagagctgcagcctcc ccagccatgacctccaccggccaggattccaccactaccagacatcgtaagagtagacac aacccccagtcgccctctcacgacttgagcattacctcgaaacgaagtgttaagaagggt gctgcaccccgctccactcccaatctagcagaaataaagaagaaaggcaagatgaagaag ctgagccaaaaagtcgaagaagacctaatcgtggggctgcaagggctggatctgaaccct gaggtcaagatagtgacgggcactggccttgtgtttgatgagcagctaaatgaattctac tgtctctgggatgacagcttccctgaaagccctgagcgactccatgccatcaaggagcag ctgatccaggagagtcttctcgatcgctgtgtgtgctttcaggcccggttcgcagaaaag gaggagctgatgttggttcacagcctagagtacattgatctgatggagatgacccagtac atgaatgagggagaactccgcgtactggcaagcacctatgattcagtttatctgcatccg aactcatactcctgtgcctgcctggcctcaggctctgttctcaggctggtagatgccgtc ctgggagctgagattcgaaatggcatggctatcatcaggcctcctggacaccatgcccag cacagtcttatggatgggtattgcatgttcaaccatgtggctgtggctgcccgctatgct caaaagaaacaccgcattcagagagtccttattgtggattgggatgtacaccacggtcaa ggaacacagttcaccttcgaccaggaccccagtgtcctctatttctctatccaccgctat gagcagggtcgattctggccccaccttaaggcctctaactggtctgccacaggttttggt caaggccaaggatacaccatcaatgtgccttggaaccaggtggggatgcgggatgccgac tacattgctgctttcctgcatatcttgctgccagttgcctttgagttccagcctcagctg gtcctagtagctgctggatttgatgccctccaaggggaccccaagggtgagatggctgcc actccagcagggtttgcccagctaacccacctactcatgggtttggcaggaggcaagctg attctgtctctagagggtggctacaaccttcactcccttgctaaaggtgtcagtgcatca ctccacacccttttgggagacccttgccccatgctggagtcccctggtgtgccctgtcga agtgcccagacttcactctcctgtactctggaagccctagaacccttctggggaatcctt gtgagatcagtagacactccagaggaggacggcgaggaggaagacactgtggaggagacc gaggaaggaccctgggaagcctctgcgctaccagtcttgacatggccagtgctgcagcat cgcactggtctggtctatgaccaaagaatgatgagtcactgcaacctatgggacaaccat caccccgagacacctcagcgtatcttgcggatcatgtgccacctggaggagctgggcctt gccgctcactgcctcatcctgcctgtgcgggctgccacagatgccgagctgctcacctgc cacagtgctgagtatgtggagcgtatccgggccacagagaagatgaagacccgggagttg caccgcgaaggtgccaactttgactccatctacctctgtcccagcaccttcacctgtgcg cagctggctgcaggcgctgcctgccgcctggtggaagctgtgctctcaggagaggttttg aacggtattgcagtggtgcgccccccaggacaccatgctgagcatgctgctgcttgcggt ttctgctttttcaactctgtggctgtggctgctcgccatgctcagaccatcagtgggcgt gccctgaggatcctgattgtggattgggacgtccatcacggcaatggaactcagcacata tttgaggatgaccccagtgtgctatatgtatccctgcaccgatatgaccgtggcaccttc ttccccatgggggatgagggtgccagcagccagataggccgggcagagggcaccggcttc actgtcaatgtaccctggaatggaccccgcgtgggtgatgctgactacctggctgcctgg catcgtcttgtgcttcctattgcctatgagtttaacccagaactggtactggtctcagct ggctttgacgctgcacgaggggacccgctaggaggttgccaggtgtcacctgagggttat gcccacctcacccacctgctgatgggccttgccaatggtcacattatccttatcctagag ggtggctacaacctgacatctatctcagagtccatggctgcctgcacccactccctcctt ggagacccgccaccactactgcccttgctgcggcctccgcaaccaggggccttggcttca atcactgagaccatccaagttcatcgcagatactggcgcagtttgcgggtcatgaaggta gaagacaaggagacatcttccgcttctaagcccgtcaccaagaaggcatcccatccaacc aatcctaaattggctaaaggggtgaccatgccagaagggaagattctgagagcaggcatg aagaaggctacctcaacattacctgcaaaagagtctactccaggacagactaaatcaaag acagctaatgtagccacactcactcaggaccagtgcttagagagagccactgggggagct aaactagaccagaccacctcagaggagactgtggaaagagccacagtggaccaaaccacc tcagaagagtctgtgggaggagccacagtgggtcaggccaccacagaggagtctgtggga gaagccacagtggaccaggccaccacagaggagtctgtggaagaagctgcagtggagcag gccaccacagaggagactgtggaaggagctacaggggacgaggccacttcagtggagtct gtgagaggagccagagtggaccaggtcaactcagaagcagccacaggggaagtcatgctg gaccagaccacttcagaggagactgcaggagaaagtgaggtgattcaaactcctctagcc tcaaacacagacaagcagactccagcagcctcacctgtgcggggagccacagcccagtca tccccctgtcagctgattgggagtcacaggattttggaactaggcaatgaaactcaggag accctagagtctcagaccctaggagaagagggcttactaggagaggcagctggaggtcag gacactgactgctcagtgctgatgcaagactttggggaacttggtgacagtgatgaggac atattttatgctgtgacaccactgtcctggtgtccccatttgggggcagtatgccccata cctgaagaaggcctggacacagctcagccttgtgaacgctgcggaacatttgaggagaac tggttgtgtttatcttgctataagatctactgtagtcgctacgtcagtgctcatatggtg tgccactttgaagcctctagacacccactggtcctcagctgtgtggacctgtctgcctgg tgttacatctgtcaggcctatgtccaccaccaggacatcctgcatgtgaagaatgttgtc caccagatcaagtttggggaggacattcctcaaccacactaa

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