Equus caballus (horse): 100146214
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Entry
100146214 CDS
T01058
Symbol
HSD17B2
Name
(RefSeq) estradiol 17-beta-dehydrogenase 2 isoform X2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00140
Steroid hormone biosynthesis
ecb01100
Metabolic pathways
ecb04913
Ovarian steroidogenesis
Module
ecb_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100146214 (HSD17B2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100146214 (HSD17B2)
Enzymes [BR:
ecb01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
100146214 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
100146214 (HSD17B2)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
DUF1776
KR
Epimerase
IcmF-related
NmrA
RmlD_sub_bind
Motif
Other DBs
NCBI-GeneID:
100146214
NCBI-ProteinID:
XP_014593952
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Position
3:30331130..30392738
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AA seq
383 aa
AA seq
DB search
MSLFCSETVGLCLAVTVVLGGAVLCKLKSPGQEGRKVVCLVGLWGGACLLSLSLFWGLLL
FSLSCCLMYTYLSGQELLPVDQKAVLITGSDSGIGHALSKHLDELGFTVFAGVLDAKGSG
AEELRRSCSKRLSVLQLDITDPQQIKDAYSKVLEKVQNRGLWAVVNNAGIICFPAEGELI
PMTHYKRCMAVNFFGAVEVTKAFLPLLRRSKGRLVSISSMAGVPMEKLAAYGSSKAALTM
FSAVMRRELSKWGIKVSVIQPGGFQTNIAGTSEMQDKLEKNLLDHLTPDVQEDYGQDYIL
AERNFLSVLNVKSQPDVSPVLRDIRHAISAKSPFAFYAPGKESYLFLCFASFVPTCVFDL
FLKNDGQSMPRALRMPNWKNKAM
NT seq
1152 nt
NT seq
+upstream
nt +downstream
nt
atgagtcttttctgctctgagacagtggggctctgcctggctgtcaccgtagtgctggga
ggagcagttctttgcaaactgaagagcccagggcaggaggggagaaaggtggtctgcttg
gtgggcctgtggggaggggcttgcctgctcagcctgtccctcttctggggcttgcttctc
ttctccctgtcatgttgcctcatgtatacttacttatccggccaagagctgttacctgtg
gatcaaaaggcggtgctgatcacaggtagcgattctgggattggccatgctttgtctaag
catctggatgagctgggcttcacagtatttgccggagttctggatgcaaagggatcagga
gcggaggaattacgaagaagctgctccaagcgcctgtctgtgctccagttggacatcact
gacccgcagcagatcaaagacgcctacagcaaagtcctggagaaggtgcagaacagagga
ctgtgggctgtggtcaacaatgctgggatcatttgcttcccagccgagggggagctcatc
cccatgacccactacaaacgatgcatggctgtgaacttctttggggcagtggaagtcacg
aaggcatttttgcctcttcttaggagatccaaagggaggctggtgagcatcagcagcatg
gcaggggtcccaatggaaaagctggcagcttatgggtcatccaaggcggctctgaccatg
ttttcggcagtcatgagacgagaactttccaaatggggaattaaagtctctgtcatccag
cccggaggcttccaaacaaatatcgcaggcacgagtgaaatgcaggacaagctggagaag
aacctcttggaccacctcaccccggacgtgcaggaagactacggccaggactatatcctc
gcagaacggaattttctcagtgtattgaacgtgaagtctcaaccagatgtctccccggtg
ctccgggacatccggcacgccatctccgctaaaagccccttcgccttttacgcaccgggg
aaggagtcttatctgttcctctgttttgcttcctttgtccctacttgcgtatttgatctt
tttctcaagaacgatggacagagcatgcccagagctctaaggatgcctaactggaagaat
aaggccatgtag
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