Felis catus (domestic cat): 101085592
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Entry
101085592 CDS
T02385
Symbol
HSD17B2
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00140
Steroid hormone biosynthesis
fca01100
Metabolic pathways
fca04913
Ovarian steroidogenesis
Module
fca_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
101085592 (HSD17B2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
101085592 (HSD17B2)
Enzymes [BR:
fca01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
101085592 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
101085592 (HSD17B2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
Epimerase
DUF1776
Motif
Other DBs
NCBI-GeneID:
101085592
NCBI-ProteinID:
XP_003998357
EnsemblRapid:
ENSFCTG00005005077
UniProt:
M3W394
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Position
E2:55365534..55457331
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AA seq
381 aa
AA seq
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MSTFSETAWLCLAVPAALGGIVLYKLKKSPGQVGRKVVCLAGLWAGAYLLSLSLFWGWVL
FPLSCFLMCAYLSGHEFLPVDQKAVLITGGDSGFGHALSKYLDELGFTVFVGVLNEKGPG
AEELRRTCSKRVSVLQMDITNPQQIKDAHSKVVEKVQNRGLWAVVNNAGIIGLPADGELI
PMTNYKQCMAVNFFGAVEVTKAFLPLLRKSKGRLVNISSMAGGVPMEKLAAYSSSKAALT
MFSAVMRQELSKWGVKVSVIQPGGFKTSIAGTSEMWNKLEQDILDNLTPEVLEDYGQDYI
LEQRDYLKFISRCANTDMSPVLLDIRHAVSAKSPFAFYSPGPMANPMLCFVSFSPTGIFD
YFSKKLHHFRGSMPKALTKQA
NT seq
1146 nt
NT seq
+upstream
nt +downstream
nt
atgagcaccttctctgagacagcatggctctgcctggctgtccccgcagcgctgggagga
atagttctttacaaactcaagaagagcccggggcaggtggggagaaaggtggtctgcctg
gcgggcctctgggcaggggcttacctgctcagcctgtccctcttctggggctgggtcctc
ttccccctgtcctgtttcctcatgtgtgcttacttatctggccacgagtttttacctgtg
gatcaaaaggcggtgctgatcacaggtggtgattctggctttggccatgccctgtccaaa
tatctggatgagcttggcttcacggtatttgtcggagttctgaatgaaaagggaccagga
gcagaggaactgcgaagaacctgctccaagcgcgtctccgtgctccagatggacatcacc
aacccgcagcagataaaagacgcccacagcaaagtggtggaaaaggtgcagaacagagga
ctgtgggctgtggtcaacaatgctgggatcattggcttaccagcggacggggagctcatt
cccatgactaactacaaacaatgcatggccgtgaacttctttggggccgtggaggtcaca
aaggcatttttgcctcttcttaggaaatccaaggggaggctggtgaacatcagcagcatg
gcaggaggggtcccaatggagaagctggcagcctatagctcatccaaggcagctctgacc
atgttttcagcagtcatgagacaagagctttccaaatggggagttaaagtctctgtcatc
cagcctggaggcttcaaaacaagtatcgcgggcacgagtgaaatgtggaacaagctggag
caggacatcctggacaaccttacccccgaagtgctagaggactatgggcaggactatatc
cttgagcaacgggattatctcaagttcatcagcaggtgtgccaacactgatatgtcccct
gtgctcctggacatccggcatgccgtgtctgctaagagcccctttgccttttactcgcca
gggccgatggctaatccaatgctctgctttgtttcatttagtcctactggcatatttgat
tattttagcaaaaagttgcatcactttagagggagcatgcccaaggcgctaactaagcag
gcctaa
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