Homo sapiens (human): 2877
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Entry
2877 CDS
T01001
Symbol
GPX2, GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2
Name
(RefSeq) glutathione peroxidase 2
KO
K00432
glutathione peroxidase [EC:
1.11.1.9
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00480
Glutathione metabolism
hsa01100
Metabolic pathways
hsa04918
Thyroid hormone synthesis
hsa05014
Amyotrophic lateral sclerosis
hsa05016
Huntington disease
hsa05022
Pathways of neurodegeneration - multiple diseases
Network
nt06026
Glutathione biosynthesis
nt06525
Ferroptosis
Element
N01589
Glutathione biosynthesis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00480 Glutathione metabolism
2877 (GPX2)
09150 Organismal Systems
09152 Endocrine system
04918 Thyroid hormone synthesis
2877 (GPX2)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
2877 (GPX2)
05016 Huntington disease
2877 (GPX2)
05022 Pathways of neurodegeneration - multiple diseases
2877 (GPX2)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.11 Acting on a peroxide as acceptor
1.11.1 Peroxidases
1.11.1.9 glutathione peroxidase
2877 (GPX2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GSHPx
Redoxin
Motif
Other DBs
NCBI-GeneID:
2877
NCBI-ProteinID:
NP_002074
OMIM:
138319
HGNC:
4554
Ensembl:
ENSG00000176153
UniProt:
P18283
Structure
PDB
LinkDB
All DBs
Position
14:complement(64939158..64942745)
Genome browser
AA seq
190 aa
AA seq
DB search
MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRR
LVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLK
DKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEP
DIKRLLKVAI
NT seq
573 nt
NT seq
+upstream
nt +downstream
nt
atggctttcattgccaagtccttctatgacctcagtgccatcagcctggatggggagaag
gtagatttcaatacgttccggggcagggccgtgctgattgagaatgtggcttcgctctga
ggcacaaccacccgggacttcacccagctcaacgagctgcaatgccgctttcccaggcgc
ctggtggtccttggcttcccttgcaaccaatttggacatcaggagaactgtcagaatgag
gagatcctgaacagtctcaagtatgtccgtcctgggggtggataccagcccaccttcacc
cttgtccaaaaatgtgaggtgaatgggcagaacgagcatcctgtcttcgcctacctgaag
gacaagctcccctacccttatgatgacccattttccctcatgaccgatcccaagctcatc
atttggagccctgtgcgccgctcagatgtggcctggaactttgagaagttcctcataggg
ccggagggagagcccttccgacgctacagccgcaccttcccaaccatcaacattgagcct
gacatcaagcgcctccttaaagttgccatatag
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