Homo sapiens (human): 840
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Entry
840 CDS
T01001
Symbol
CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3
Name
(RefSeq) caspase 7
KO
K04397
caspase 7 [EC:
3.4.22.60
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04148
Efferocytosis
hsa04210
Apoptosis
hsa04215
Apoptosis - multiple species
hsa04623
Cytosolic DNA-sensing pathway
hsa04668
TNF signaling pathway
hsa04932
Non-alcoholic fatty liver disease
hsa05010
Alzheimer disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05130
Pathogenic Escherichia coli infection
hsa05132
Salmonella infection
hsa05133
Pertussis
hsa05134
Legionellosis
hsa05200
Pathways in cancer
hsa05417
Lipid and atherosclerosis
Network
nt06161
Human immunodeficiency virus 1 (HIV-1)
nt06162
Hepatitis B virus (HBV)
nt06163
Hepatitis C virus (HCV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06166
Human papillomavirus (HPV)
nt06167
Human cytomegalovirus (HCMV)
nt06168
Herpes simplex virus 1 (HSV-1)
nt06170
Influenza A virus (IAV)
nt06231
Apoptosis (cancer)
nt06260
Colorectal cancer
nt06263
Hepatocellular carcinoma
nt06267
Small cell lung cancer
nt06460
Alzheimer disease
nt06461
Huntington disease
nt06462
Spinocerebellar ataxia
nt06463
Parkinson disease
nt06464
Amyotrophic lateral sclerosis
nt06465
Prion disease
nt06466
Pathways of neurodegeneration
nt06516
TNF signaling
nt06524
Apoptosis
nt06528
Calcium signaling
nt06535
Efferocytosis
Element
N00098
Intrinsic apoptotic pathway
N00100
BCL2-overexpression to intrinsic apoptotic pathway
N00145
Extrinsic apoptotic pathway
N00146
Crosstalk between extrinsic and intrinsic apoptotic pathways
N00967
VGCC-Ca2+ -apoptotic pathway
N00984
mGluR5-Ca2+ -apoptotic pathway
N00985
Mutation-caused aberrant Htt to mGluR5-Ca2+ -apoptotic pathway
N01007
Mutation-caused aberrant PSEN to mGluR5-Ca2+ -apoptotic pathway
N01747
Find-me signal (nucleotide)
N01750
Find-me signal (S1P)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
840 (CASP7)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
840 (CASP7)
09143 Cell growth and death
04210 Apoptosis
840 (CASP7)
04215 Apoptosis - multiple species
840 (CASP7)
09150 Organismal Systems
09151 Immune system
04623 Cytosolic DNA-sensing pathway
840 (CASP7)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
840 (CASP7)
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
840 (CASP7)
05132 Salmonella infection
840 (CASP7)
05133 Pertussis
840 (CASP7)
05134 Legionellosis
840 (CASP7)
09164 Neurodegenerative disease
05010 Alzheimer disease
840 (CASP7)
05022 Pathways of neurodegeneration - multiple diseases
840 (CASP7)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
840 (CASP7)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
840 (CASP7)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
840 (CASP7)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.22 Cysteine endopeptidases
3.4.22.60 caspase-7
840 (CASP7)
Peptidases and inhibitors [BR:
hsa01002
]
Cysteine peptidases
Family C14: caspase family
840 (CASP7)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_C14
EZH2_N
Motif
Other DBs
NCBI-GeneID:
840
NCBI-ProteinID:
NP_001218
OMIM:
601761
HGNC:
1508
Ensembl:
ENSG00000165806
UniProt:
P55210
Structure
PDB
LinkDB
All DBs
Position
10:113679194..113730909
Genome browser
AA seq
303 aa
AA seq
DB search
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
FSQ
NT seq
912 nt
NT seq
+upstream
nt +downstream
nt
atggcagatgatcagggctgtattgaagagcagggggttgaggattcagcaaatgaagat
tcagtggatgctaagccagaccggtcctcgtttgtaccgtccctcttcagtaagaagaag
aaaaatgtcaccatgcgatccatcaagaccacccgggaccgagtgcctacatatcagtac
aacatgaattttgaaaagctgggcaaatgcatcataataaacaacaagaactttgataaa
gtgacaggtatgggcgttcgaaacggaacagacaaagatgccgaggcgctcttcaagtgc
ttccgaagcctgggttttgacgtgattgtctataatgactgctcttgtgccaagatgcaa
gatctgcttaaaaaagcttctgaagaggaccatacaaatgccgcctgcttcgcctgcatc
ctcttaagccatggagaagaaaatgtaatttatgggaaagatggtgtcacaccaataaag
gatttgacagcccactttaggggggatagatgcaaaacccttttagagaaacccaaactc
ttcttcattcaggcttgccgagggaccgagcttgatgatggcatccaggccgactcgggg
cccatcaatgacacagatgctaatcctcgatacaagatcccagtggaagctgacttcctc
ttcgcctattccacggttccaggctattactcgtggaggagcccaggaagaggctcctgg
tttgtgcaagccctctgctccatcctggaggagcacggaaaagacctggaaatcatgcag
atcctcaccagggtgaatgacagagttgccaggcactttgagtctcagtctgatgaccca
cacttccatgagaagaagcagatcccctgtgtggtctccatgctcaccaaggaactctac
ttcagtcaatag
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