Lepisosteus oculatus (spotted gar): 102692720
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Entry
102692720 CDS
T07349
Symbol
hsd17b2
Name
(RefSeq) estradiol 17-beta-dehydrogenase 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
loc
Lepisosteus oculatus (spotted gar)
Pathway
loc00140
Steroid hormone biosynthesis
loc01100
Metabolic pathways
Module
loc_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
loc00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
102692720 (hsd17b2)
Enzymes [BR:
loc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
102692720 (hsd17b2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
102692720 (hsd17b2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Epimerase
Motif
Other DBs
NCBI-GeneID:
102692720
NCBI-ProteinID:
XP_015223426
Ensembl:
ENSLOCG00000002170
UniProt:
W5M2B9
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Position
LG23:3003045..3012935
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AA seq
399 aa
AA seq
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MDTSFSESLYFLMLYASITTLYAGAVILRVKGGLKLGSWSLIWCLLLAVLVEPLCFLKVP
GYAGLLLLSLLYYISLSLLGKSQKLLPVNNKSVLITGCDSGFGHALAKHLDSLGVTVFAG
VLNEQSPGSDELRRCSSKRLLVLQLDVTNSAQIRKAYQQIQAEVGETGLWAIVNNAGILG
YLADGEILPMTVFKKCMAVNFLGAVELSQTFLPLLRRARGRMVNVSSMAAKVPVPMFSAY
CASKAALSMFSEVMRHELSSWGIRVSVIQPGGFRTNIFGTREEWSCYQEEILSQVPQDVK
EDYGEEYISSFQKRMPKMSAVSSVDLWPVVHNICHALLAVRPEHVYAPGRLASVIPFVHS
FFPASVSDLLIGVFFKFHKDAPARLQRSTGSAKGEREHN
NT seq
1200 nt
NT seq
+upstream
nt +downstream
nt
atggatacatctttcagtgaatctttgtacttcctgatgctgtatgcttctataacaaca
ttgtatgcaggggcagtaatattgagagtgaaagggggtctgaaactggggtcttggtct
ttgatctggtgccttctcttggctgtcctggtggagcccctgtgctttctgaaggtcccg
ggttatgctgggctactcctgctctccttgctctactacatttcattgtcactcctggga
aaatcgcagaagctgctacctgtgaacaataagagtgtgctgattacaggctgtgattca
ggtttcggtcatgccttggctaagcacttggacagcctgggtgtgaccgtgtttgctggg
gtcttaaatgagcagagtcccggctctgatgaactgaggaggtgtagctcaaagagactt
cttgtgctgcagctggatgtgaccaacagtgcacagatcaggaaggcctaccagcaaatt
caagctgaagtgggcgaaacaggactttgggcaatagtgaataatgcaggaatcctggga
tatttagcagatggagaaattcttcccatgacagtgtttaaaaagtgcatggcggtcaac
ttcctgggtgctgtggagctgtcccagacattcctgcccctgctgcgcagagccagaggc
aggatggtcaacgtttcaagtatggcagccaaggttccagtccctatgttctctgcctat
tgtgcctccaaagcagccctgagcatgttttctgaggtgatgagacatgaactatccagt
tggggcatcagagtctctgttatccagcctggaggtttcagaacaaacatctttggcaca
agggaggaatggagctgctatcaggaagagattctctcccaggtcccgcaggacgttaaa
gaggactacggggaagagtacatctcctcctttcagaagcgcatgcccaagatgtctgca
gtctcctcggtggatttgtggcctgtggtccacaacatctgccatgccctgctggcggtg
cgccccgagcacgtctacgctccgggcaggctagcgagcgtcatcccattcgtccacagc
ttcttccctgccagcgtctccgacctcctcatcggagttttcttcaagttccacaaggat
gctccggcacgcctccagaggagcaccgggtcagccaagggggaacgagagcacaactag
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