KEGG   Mirounga leonina (Southern elephant seal): 118000167
Entry
118000167         CDS       T07472                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx04010  MAPK signaling pathway
mlx04015  Rap1 signaling pathway
mlx04218  Cellular senescence
mlx04620  Toll-like receptor signaling pathway
mlx04664  Fc epsilon RI signaling pathway
mlx04668  TNF signaling pathway
mlx04714  Thermogenesis
mlx04750  Inflammatory mediator regulation of TRP channels
mlx04912  GnRH signaling pathway
mlx04935  Growth hormone synthesis, secretion and action
mlx04936  Alcoholic liver disease
mlx05014  Amyotrophic lateral sclerosis
mlx05022  Pathways of neurodegeneration - multiple diseases
mlx05132  Salmonella infection
mlx05135  Yersinia infection
mlx05145  Toxoplasmosis
mlx05161  Hepatitis B
mlx05169  Epstein-Barr virus infection
mlx05170  Human immunodeficiency virus 1 infection
mlx05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mlx05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118000167 (MAP2K3)
   04015 Rap1 signaling pathway
    118000167 (MAP2K3)
   04668 TNF signaling pathway
    118000167 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    118000167 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    118000167 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    118000167 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    118000167 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    118000167 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    118000167 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    118000167 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118000167 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    118000167 (MAP2K3)
   05161 Hepatitis B
    118000167 (MAP2K3)
   05169 Epstein-Barr virus infection
    118000167 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118000167 (MAP2K3)
   05135 Yersinia infection
    118000167 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    118000167 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    118000167 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    118000167 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118000167 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    118000167 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlx01001]
    118000167 (MAP2K3)
Enzymes [BR:mlx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     118000167 (MAP2K3)
Protein kinases [BR:mlx01001]
 Serine/threonine kinases: STE group
  STE7 family
   118000167 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Seadorna_VP7 Pkinase_fungal APH DUF4344 Choline_kinase RIO1
Other DBs
NCBI-GeneID: 118000167
NCBI-ProteinID: XP_034845679
LinkDB
Position
Unknown
AA seq 347 aa
MESPASSQPASMPQTKGKSKRKKDIRISFVSKPPVPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHNQSDTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTLDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcccgcctccagtcagcccgccagcatgccccagaccaaagggaaatccaaa
aggaagaaggatatacggatatccttcgtgtccaagccgcccgtacccaaccccacaccc
ccccggaaccttgactcccggaccttcatcaccatcggagacaggaactttgaggtggag
gctgatgacctggtgaccatctcggagctgggccgtggggcctacggggtggtggagaag
gtgcggcataaccagagcgacaccatcatggccgttaagcggatccgggccaccgtgaac
tcacaggagcagaagcgtctgctcatggacttggacatcaacatgcgcacggtcgactgc
ttctacaccgtcaccttctatggggccctgttcagagagggagatgtgtggatctgcatg
gagctcatggacacgtccctggacaagttctaccggaaggtgctcgataaaaacatgacc
attccggaggacatcctgggggaaattgctgtgtctatcgtgagggcgctggagcatctg
cacagcaagctgtccgtgatccacagagacgtgaagccgtccaatgtcctcatcaacaag
gagggtcacgtgaagatgtgcgactttgggattagtggctacttggtggattctgtggcc
aaaacgctggacgctggctgcaaaccctacatggctcccgagaggatcaacccggagctg
aaccagaagggctacaatgtcaagtctgatgtctggagcctcggcatcaccatgatcgag
atggccatcctccgctttccgtacgaatcctgggggactccgttccagcagctgaagcag
gtggtggaagagccgtctccccagctcccagctgaccgtttctctcctgagtttgtggac
ttcactgcgcagtgcctgaggaagaaccctgcggagcgcatgagctacttggagctgatg
gagcacccattcttcacgttgcacaaaacgaagaagacggacattgcggcctttgtgaag
gagatcctgggggaggactcctag

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