Marmota marmota marmota (Alpine marmot): 107157473 Help Entry 107157473         CDS       T09644                                  Symbol Insr Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism mmma  Marmota marmota marmota (Alpine marmot) Pathway mmma04010   MAPK signaling pathway mmma04014   Ras signaling pathway mmma04015   Rap1 signaling pathway mmma04022   cGMP-PKG signaling pathway mmma04066   HIF-1 signaling pathway mmma04068   FoxO signaling pathway mmma04072   Phospholipase D signaling pathway mmma04150   mTOR signaling pathway mmma04151   PI3K-Akt signaling pathway mmma04152   AMPK signaling pathway mmma04211   Longevity regulating pathway mmma04213   Longevity regulating pathway - multiple species mmma04520   Adherens junction mmma04910   Insulin signaling pathway mmma04913   Ovarian steroidogenesis mmma04923   Regulation of lipolysis in adipocytes mmma04930   Type II diabetes mellitus mmma04931   Insulin resistance mmma04932   Non-alcoholic fatty liver disease mmma04960   Aldosterone-regulated sodium reabsorption mmma05010   Alzheimer disease mmma05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:mmma00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     107157473 (Insr)    04014 Ras signaling pathway     107157473 (Insr)    04015 Rap1 signaling pathway     107157473 (Insr)    04066 HIF-1 signaling pathway     107157473 (Insr)    04068 FoxO signaling pathway     107157473 (Insr)    04072 Phospholipase D signaling pathway     107157473 (Insr)    04022 cGMP-PKG signaling pathway     107157473 (Insr)    04151 PI3K-Akt signaling pathway     107157473 (Insr)    04152 AMPK signaling pathway     107157473 (Insr)    04150 mTOR signaling pathway     107157473 (Insr)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     107157473 (Insr)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     107157473 (Insr)    04923 Regulation of lipolysis in adipocytes     107157473 (Insr)    04913 Ovarian steroidogenesis     107157473 (Insr)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     107157473 (Insr)   09149 Aging    04211 Longevity regulating pathway     107157473 (Insr)    04213 Longevity regulating pathway - multiple species     107157473 (Insr)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     107157473 (Insr)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     107157473 (Insr)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     107157473 (Insr)    04932 Non-alcoholic fatty liver disease     107157473 (Insr)    04931 Insulin resistance     107157473 (Insr)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mmma01001]     107157473 (Insr)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:mmma04090]     107157473 (Insr) Enzymes [BR:mmma01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      107157473 (Insr) Protein kinases [BR:mmma01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    107157473 (Insr) CD molecules [BR:mmma04090]  Proteins   107157473 (Insr) BRITE hierarchy Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  107157473 NCBI-ProteinID:  XP_048668824 Ensembl:  ENSMMMG00000020292 LinkDB All DBs Position Unknown AA seq 1346 aa AA seqDB search MDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIIITDYLLLFRVYGLE SLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLAT IDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQK VCPTICKSHGCTAEGLCCHSECLGNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQD WRCVNFSFCQDLHNRCKNSRRPGCHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPK VCHLLEGEKTIDSVTSAQELRGCTVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKI RRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHY NPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSFIKTSFDKILLKWE PYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPQRSNDPKPQHHPG WLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQ IILKWKPPSDPNGNITHYLVYWERQEEDSELYELDYCLKGLKLPSRTWSPPFESDDSQKH NQSEYEDSAGECCTCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGSSAEDHRP SRKRRSLGVEANVTEPVPTAPAPALPSSSPSAPASQEEHRPFEKVVNKESLVISGLRHFT GYRIELQACNQDAPEARCSVAAYVSARTMPEAKADDIIGPVTHEIFENNVVHLMWQEPKE PNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRIRATSLAGNGSW TEATYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSN PEYLSASDVFPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAV KTVNEAASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLR SLRPEAENNPGRPPPTLQEVIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIG DFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTASSDMWSFGVVLWEITSLAEQP YQGLSNEQVLKFVMDGGYLEQPDNCPDTVTELMRMCWQFNPKMRPTFLEIVNLLKDDLHP SFPEVSFFHSDENKAPESEELEMEFEDMENVPLDRSSHCQREEAGGREGGSSLGIKRNYE DHIPYTHMNGGKKNGRILTLPRSSPS NT seq 4041 nt NT seq  +upstreamnt  +downstreamnt atggacatccggaacaacctcaccaggctgcatgaactggagaactgctcggtcatcgag ggacacctgcagatcctgctgatgttcaaaaccaggcccgaggacttccgggacctcagc ttccccaagctcatcatcatcaccgactacctgctgctcttccgcgtctacgggctggag agcctcaaggacctgttccccaacctcacggtcatccgcggctcccgcctcttcttcaac tacgcgctggtcatcttcgagatggtccacctgaaggagctggggctctacagcctcatg aacatcacccggggctccgtgcgcatcgagaagaacaacgagctctgctacctggccacc atcgactggtcccggatcctggactccgtggaggacaactacatcgtgctgaacaaagac gacaacgaggagtgcggagacatctgcccgggcaccgccaagggcaagaccaactgcccc gccaccgtcatcaacgggcagtttgtcgagcggtgctggacgcacagccattgccagaaa gtttgcccgaccatctgtaagtcgcacggctgtaccgccgaagggctctgctgccacagc gaatgcttgggcaactgttccgagcccgatgatcccaccaagtgtgttgcctgccgcaac ttctacctggacggcaggtgcgtggagacctgcccgcccccctactaccacttccaggac tggcgctgcgtgaacttcagcttctgccaggatctgcacaacagatgcaagaactcccgc cgcccgggctgccaccagtacgtcatccacaacaacaaatgcatccccgaatgtccttcg ggctacaccatgaactccagcaacttgatgtgtaccccatgcctgggcccctgtcccaag gtctgtcacctcctagaaggcgagaagaccatcgactcggtgacgtcggcccaggagctc cgaggctgcaccgtggtcaacgggagcctgatcatcaacatccgcgggggcaacaatctg gcggctgagctggaggccaacctcggcctcattgaagaaatttcaggatatctcaaaatc cgccgatcctacgctctggtgtccctctccttcttccggaagttgcgtctgattcgagga gagacgctggagatcgggaattactctttctacgccttggacaaccagaacctgaggcag ctctgggactggagcaagcacaacctcaccatcactcaggggaaactcttcttccactat aatcccaaactctgcctgtcggaaattcacaagatggaagaagtctctggaaccaagggg cgccaggagaggaatgacattgccctgaagaccaacggggaccaggcatcttgtgaaaat gaattacttaaattttctttcattaagacatcttttgacaagatcttgctgaaatgggag ccgtactggcctcctgacttccgggacctcttaggatttatgctcttctacaaagaggcc ccttatcagaacgtgaccgagtttgacgggcaggatgcatgtggctccaacagctggact gtggtggacatcgacccgcctcagaggtctaacgaccccaagccccagcaccaccccgga tggctgatgcggggtctcaagccctggacccagtacgccatctttgtcaagactttggtc accttttctgatgagcgccggacctacggggccaagagtgacatcatctatgtgcagaca gatgccaccaatccttccgtccccctggatcccatctcggtttcgaattcctcgtctcag atcatcttgaagtggaagcccccctcggaccccaacggcaacatcacgcactacctggtt tactgggaaaggcaggaggaagacagtgagctgtacgagttggattattgtctcaaaggc ttgaagctgccctcgcgcacgtggtccccgccgttcgagtcggacgattctcagaagcac aatcagagcgagtacgaggactcggccggggagtgctgcacctgcccgaagaccgactct cagattctgaaggagctggaggagtcctcgtttcggaagacctttgaggattacctgcac aacgtcgttttcgtccccagaaaaacctcttcaggcagtagtgccgaggatcatagaccg tctcggaaacgcaggtcccttggtgtcgaggcgaacgtgacggagcccgtgcccacggcc ccagccccggccctccccagcagctcccccagcgcgcccgccagccaggaggagcacagg ccctttgagaaggtggtcaacaaggagtcgctggtcatctctggcctgcgccacttcacc ggctaccgcatcgagctgcaggcctgcaaccaggacgcgcccgaggcgaggtgcagcgtg gccgcctacgtgagcgcgcgcaccatgcccgaagccaaggcagatgacatcatcggccct gtgacccacgaaatcttcgagaacaacgttgttcacttgatgtggcaagagcccaaggaa cccaatggtcttatcgtgctgtatgaagtgagttatcggcgctatggtgatgaggagctg catctctgtgtctcccggaagcactttgctctggagaggggctgcaggctgcgtgggctg tcaccagggaactatagcgtgcgcatccgggccacctccctggcaggcaatggctcctgg acagaagccacttatttctacgtgaccgattatctagatgtgccatcaaatattgccaaa atcatcattggccctctcatctttgtctttctcttcagtgttgtgattggaagcatttac ctgttcttgagaaaaaggcagccagatgggccgatgggacctctctatgcttcttcaaac cccgagtacctcagcgccagtgacgtgttcccctcttctgtgtatgtgccggacgaatgg gaggtgcctcgggagaagatcaccctcctgcgggagctggggcagggctccttcggcatg gtgtacgagggcaatgccaaggacatcatcaagggcgaggcagagacccgggtggcagtg aagaccgtcaacgaggcagccagtctccgggagcggattgagttcctcaatgaggcctcg gtcatgaagggcttcacctgccatcatgtggtccgcctcctgggggtggtgtccaagggc cagcccacgctggtggtgatggagctgatggctcacggagacctgaagagctacctccgc tctctgaggccggaggctgagaataaccccggccgccctcccccgaccctgcaagaggtg attcagatggcagcagagatcgcagatgggatggcatacttgaatgccaagaagtttgtg caccgggacctggcagctcgaaactgcatggttgctcatgattttactgtcaaaattgga gattttggaatgaccagagacatctacgaaacggattactaccggaaagggggcaagggc ctgctgcccgtgcggtggatggcacccgagtccctgaaggacggggtctttaccgcttct tctgacatgtggtccttcggtgtggtcctctgggagatcaccagcctggcggaacagccc taccaaggcctgtctaacgagcaggtgctcaagttcgtcatggacggcgggtacctggag cagcccgacaactgtccagatacagtcaccgagctgatgcgcatgtgctggcagttcaac cccaagatgcggcccaccttcctggaaatcgtcaacctgctcaaggatgacctgcacccc agctttccagaagtttccttcttccacagtgatgagaacaaggctcccgagagtgaggag ctggagatggagtttgaggacatggagaatgtccccttggatcggtcctcccactgtcag agggaggaggctgggggccgggagggagggtcctcgctgggcatcaagcggaactatgag gaccacatcccctacacccacatgaacgggggcaagaagaacgggcggattctgaccttg ccccggtccagtccttcctaa

DBGET integrated database retrieval system